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Indian Journal of Emergency Medicine 12(2):p 92-96, April-June 2026. | DOI: https://doi.org/10.21088/ijem.2395.311X.12226.6
Case Report
An Unusual Coexistence of Single Vessel Coronary Artery Disease and Hypokalaemia Periodic Paralysis
Girish Kulle, Anita Rawat, Kishalay Datta
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Emergency Medicine 12(2):p 92-96, April-June 2026. | DOI: https://doi.org/10.21088/ijem.2395.311X.12226.6
How Cite This Article:
Girish Kulle, Anita Rawat, Kishalay Datta. An Unusual Coexistence of Single Vessel Coronary Artery Disease and Hypokalaemia Periodic Paralysis. Ind J Emerg Med. 2026; 12(2): 92-96.Timeline
Received : January 17, 2026
Accepted : February 20, 2026
Published : June 30, 2026
Abstract
We present a rare case highlighting the unusual coexistence of single vessel coronary artery disease (CAD) and hypokalemic periodic paralysis (HPP) in a middle-aged male. The patient presented to the emergency department with acute onset chest discomfort, generalized muscle weakness, and difficulty in mobility. Initial evaluation revealed hypokalemia, confirmed on serum electrolyte analysis, alongside electrocardiographic changes suggestive of myocardial ischemia. Subsequent coronary angiography demonstrated significant stenosis of a single major coronary artery. HPP, a channelopathy characterized by recurrent episodes of muscle weakness due to low serum potassium, is rarely reported in conjunction with structural cardiac disease such as CAD. This unique presentation posed a diagnostic and therapeutic challenge, as both conditions required simultaneous yet cautious management to avoid exacerbation of either pathology. Potassium replacement therapy resulted in complete neurological recovery, while percutaneous coronary intervention addressed the underlying ischemic burden. This case underscores the importance of considering concurrent metabolic and structural cardiac disorders in patients with atypical presentations, and highlights the need for integrated, multidisciplinary management to optimize outcomes. To our knowledge, documented reports of such coexistence remain scarce, making this case a valuable contribution to the literature.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Girish Kulle, Anita Rawat, Kishalay Datta. An Unusual Coexistence of Single Vessel Coronary Artery Disease and Hypokalaemia Periodic Paralysis. Ind J Emerg Med. 2026; 12(2): 92-96.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| January 17, 2026 | February 20, 2026 | June 30, 2026 |
DOI: https://doi.org/10.21088/ijem.2395.311X.12226.6
Keywords
Coronary Artery DiseaseHypokalaemia Periodic ParalysisSearch for Similar Articles
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Timeline
| Received | January 17, 2026 |
| Accepted | February 20, 2026 |
| Published | June 30, 2026 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
