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Case Report

Beyond Cirrhosis: When Pancreas Bleed

Apurva Sahay, Kishalay Datta, Surjeet Acharya

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Indian Journal of Emergency Medicine 12(2):p 97-100, April-June 2026. | DOI: https://doi.org/10.21088/ijem.2395.311X.12226.7

How Cite This Article:

Apurva Sahay, Kishalay Datta, Surjeet Acharya. Beyond Cirrhosis: When Pancreas Bleed. Ind J Emerg Med. 2026; 12(2): 97-100

Timeline

Received : January 23, 2026         Accepted : February 25, 2026          Published : June 30, 2026

Abstract

Pancreatic cancer is a highly aggressive malignancy with poor prognosis, largely due to its silent onset and delayed diagnosis. Patients typically present with vague symptoms such as abdominal discomfort, jaundice, anorexia, and weight loss. Uncommonly, pancreatic malignancy may initially manifest as upper gastrointestinal bleeding, a presentation that can obscure the underlying diagnosis. One rare but important mechanism for such bleeding is splenic vein thrombosis, which leads to left-sided portal hypertension and the development of isolated gastric varices. Unlike portal hypertension due to chronic liver disease, this condition spares the liver and oesophagus, making recognition challenging. In the emergency setting, patients presenting with melena or hematemesis in the absence of liver dysfunction, ascites, or abnormal liver function tests often prompt diagnostic uncertainty. Cross-sectional imaging with contrast-enhanced CT or MRI plays a crucial role in identifying splenic vein thrombosis and associated pancreatic pathology. Tumours involving the pancreatic tail are particularly prone to causing venous compression or invasion, resulting in thrombosis. Management differs from conventional variceal bleeding, as endoscopic therapy provides only temporary control. Definitive treatment requires addressing the underlying cause, often through distal pancreatectomy with splenectomy in resectable disease. This report highlights pancreatic cancer as a rare but critical cause of isolated gastric variceal bleeding and emphasizes the importance of maintaining a high index of suspicion to enable timely diagnosis and potentially curative intervention.


References

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  • 2.   Victor D.W. III, Nguyen K., Zhang D.S., et al. Massive Gastric Variceal Hemorrhage Due to Splenic Vein Thrombosis: A Rare Initial Presentation of Asymptomatic Metastatic Pancreatic Adenocarcinoma. J Liver Res Disord Ther. 2018; 4(3): 121-122.
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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Apurva Sahay, Kishalay Datta, Surjeet Acharya. Beyond Cirrhosis: When Pancreas Bleed. Ind J Emerg Med. 2026; 12(2): 97-100


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
January 23, 2026 February 25, 2026 June 30, 2026

DOI: https://doi.org/10.21088/ijem.2395.311X.12226.7

Keywords

CirrhosisPancreatic cancerGastric varicesVariceal bleed

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Received January 23, 2026
Accepted February 25, 2026
Published June 30, 2026

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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