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An Observational Study to Compare Effects of Dexmedetomidine with Levobupivacaine 0.5% and Levobupivacaine 0.5% alone for SCBP Block for Upper Limb Surgeries

Tejash H Sharma , Karnavat Dhruval N1 , Sharma Tejash H2 , Chauhan Dinesh K3

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Indian Journal of Anesthesia and Analgesia 6(2):p 423-428, MARCH-APRIL 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6219.8

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Karnavat Dhruval N, Sharma Tejash H, Chauhan Dinesh K. An Observational Study to Compare Effects of Dexmedetomidine with Levobupivacaine 0.5% and Levobupivacaine 0.5% alone for SCBP Block for Upper Limb Surgeries. Indian J Anesth Analg. 2019;6(2):423-428.

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Abstract

Context: Dexmedetomidine, a potent α2 adrenoceptor agonist, is more selective towards the α2 adrenoceptor and have analgesic and sedative properties [3]. Levobupivacaine has been shown to be safe and effective for epidural/spinal anaesthesia and brachial plexus block [4]. Aims: To assess the safety, efficacy, onset & duration of sensory & motor block and rescue analgesia time of dexmedetomidine as an adjuvant to levobupivacaine 0.5% and levobupivacaine 0.5% alone in supraclavicular brachial plexus (SCBP) block. Material and methods: 60 patients aged 18-55 years of ASA I & II were divided randomly into two groups using chit method. Group LD (n=30) received 0.5% levobupivacaine 30 ml with inj. dexmedetomidine 1 μg kg-1 and Group L (n=30) 0.5% levobupivacaine 30 ml alone in SCBP block. Onset and duration of sensory & motor block, as well as duration of analgesia were assessed using pinprick, bromage score and visual analogue score respectively. Statistical analysis: The statistical analysis was assessed by unpaired t-test on Microsoft excel and IBM SPSS (Statistical Package for Social Sciences) version 21. P-value significant if <0.05. Results: The rescue analgesia time for Group LD was 1029.55 ± 95.87 and Group L was 657.93 ± 47.81 (p<0.0001). The onset of sensory & motor block was hastened, while duration was significantly prolonged in Group LD than Group L. Conclusion: Dexmedetomidine when added to levobupivacaine in SCBP block hastens the onset and prolongs duration of sensory & motor block and rescue analgesia time in the postoperative period with steady haemodynamics.

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Karnavat Dhruval N, Sharma Tejash H, Chauhan Dinesh K. An Observational Study to Compare Effects of Dexmedetomidine with Levobupivacaine 0.5% and Levobupivacaine 0.5% alone for SCBP Block for Upper Limb Surgeries. Indian J Anesth Analg. 2019;6(2):423-428.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6219.8

Keywords

Dexmedetomidine; 0.5% Levobupivacaine; Supraclavicular Brachial Plexus Block.

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