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An Observational Study to Compare Dexmedetomidine and Clonidine as Adjuvant to Local Anaesthetic Ropivacaine (0.5%) in Supraclavicular Brachial Plexus Block for Upper Limb Surgery

Dr. Dinesh Chauhan, Professor and Head, Dept. of Anesthesiology, Smt. B.K. Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth, Pipaira, Vadodara, Gujarat 391760, India. , Priyanka Singla1 , Dinesh Chauhan2

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Indian Journal of Anesthesia and Analgesia 5(4):p 604-609, April 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.16

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Abstract

Context: Various adjuvants have been used with Ropivacaine in supraclavicular blocks to enhance sensory and motor block along with prolongation of postoperative analgesia.

Aim: To compare the effect of dexmedetomidine and clonidine as adjuvant to 0.5% ropivacaine in supraclavicular brachial plexus block with respect to onset and duration of sensory and motor block and duration of analgesia.

Methods and Material: After ethical committee’s approval, a prospective randomised study of 60 patients aged1860 years were randomly divided into two groups (Group C and Group D) of 30 each. Group C received 50mcg clonidine with ropivacaine (29ml), Group D received 50mcg dexmedetomidine with ropivacaine (29ml), via supraclavicular approach. Onset and duration of sensory and motor block and duration of analgesia in both groups were evaluated. Intraoperative hemodynamics and adverse effects were observed.

Statistical Analysis: Numericalvariables were presented as mean & standarddeviation while categoricalvariables were presented as frequency and percent. For analysis, unpaired student ttest and chisquare test were used.

Results: Early onset and prolonged duration of sensory and motor block and prolonged duration of analgesia was seen in group D, as compared to group C.

Conclusion: Dexmedetomidine produces rapid onset and prolonged duration of sensory and motor block and also prolonged duration of analgesia with good hemodynamic stability with no side effects as compared to clonidine.

 

 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.16

Keywords

Dexmedetomidine; Clonidine; Ropivacaine; Brachial Plexus Block. 

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