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Case Report

Advanced Adenoid Cystic Carcinoma with Widespread Visceral and Skeletal Metastases

Virendra Bhandari, Pradumn Mishra, Rishabh Mahajan, Nayantara Pitaliya, Ashar Iqbal Lodi, Sagun Sagar Bajpai

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Indian Journal of Cancer Education and Research 13(2):p 89-92, July-Dec 2025. | DOI: https://doi.org/10.21088/ijcer.2321.9815.13225.6

How Cite This Article:

Pradumn Mishra, Rishabh Mahajan, Nayantara Pitaliya, et al. Advanced Adenoid Cystic Carcinoma with Widespread Visceral and Skeletal Metastases. Ind J Canc Educ Res 2025; 13(2): 89-92.

Timeline

Received : August 28, 2025         Accepted : October 29, 2025          Published : December 30, 2025

Abstract

Context: Adenoid cystic carcinoma (ACC) is a rare malignancy of secretory glands, characterized by an indolent yet relentless course with high rates of local recurrence and distant metastases. Case: We present a case of a 40-year-old male diagnosed in 2019 with nasal ACC, who developed widespread metastases to lungs, liver, bones, peritoneum, and lymph nodes despite multiple surgeries and targeted therapies. Progression continued on lenvatinib, lenalidomide, and axitinib. Patient received palliative radiotherapy for painful skeletal lesions. Conclusion: This case highlights the aggressive nature of ACC in advanced stages and underscores the role of palliation when systemic therapies fail.


References

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This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

Information not provide.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Pradumn Mishra, Rishabh Mahajan, Nayantara Pitaliya, et al. Advanced Adenoid Cystic Carcinoma with Widespread Visceral and Skeletal Metastases. Ind J Canc Educ Res 2025; 13(2): 89-92.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
August 28, 2025 October 29, 2025 December 30, 2025

DOI: https://doi.org/10.21088/ijcer.2321.9815.13225.6

Keywords

Adenoid cystic carcinomaMetastatic ACCTargeted therapyVEGF inhibitorsPalliative radiotherapy

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Received August 28, 2025
Accepted October 29, 2025
Published December 30, 2025

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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