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A Study on the Efficacy of Single Dose Intravenous Paracetamol and Intravenous Fentanyl for Intraoperative and Postoperative Pain Relief in Dilatation and Evacuation

Mary Samuel, Professor, Department of Anaesthesiology, Dr. D.Y. Patil Medical College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pimpri Pune Maharashtra 400018, India. , Deepasri Chowdhury1 , Mary Samuel2 , Azhar Mubarak3

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Indian Journal of Anesthesia and Analgesia 5(11):p 1846-1853, November-December 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.12

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Abstract

  Background and Aims: Dilatation and evacuation is a common Obstetrics day care procedure. However, it is a painful experience for the woman both during the intraoperative and postoperative period. Hence the purpose of this study was to compare single dose intravenous Paracetamol and intravenous Fentanyl for intraoperative and postoperative pain relief in dilatation and evacuation. Materials and Method: Sixty female patients were randomly included and divided into two groups of 30 patients each. Group P received intravenous (IV) paracetamol 15 mg/kg in the preoperative waiting area 15 min before starting the procedure. Group F received IV fentanyl 2 mcg/kg at induction of anaesthesia. Intraoperative and postoperative vitals along with postoperative pain scores on a numerical rating scale at 5, 15, and 30 min intervals after surgery were recorded. Results: Pain scores observed with paracetamol were not significantly different from that of fentanyl. Side effects were observed less with paracetamol.

Conclusion: The study demonstrates the usefulness of IV paracetamol which may be as effective as fentanyl in dilation and evacuation procedures without the major side effects of fentanyl.Paracetamol is also more cost effective. 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.12

Keywords

Dilatation and Evacuation; Pain Relief; Paracetamol; Fentanyl. 

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