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A Short Introduction on Network Pharmacology: Overview on BioactivesTargets-Pathways Interaction

Pukar Khanal , Pukar Khanal

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Indian Journal of Diabetes and Endocrinology 2(2):p 79-81, July - December 2020. | DOI:

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Pukar Khanal / A Short Introduction on Network Pharmacology: Overview on Bioactives-Targets-Pathways Interaction. Indian Journal of Diabetes and Endocrinology. 2020;2(2):79-81


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Abstract

Presently, network pharmacology is being  popular in investigating the probable interaction of  secondary metabolites from herbal medicines with  multiple proteins involved in the various disease  pathogenesis and understanding the probable  molecular mechanism. The concept is based on  the multi compound-multi protein interaction and  somewhat different from a lock and key concept  of drug discovery. In this context, this minireview highlights the major aspects of network  pharmacology during the conceptualization of  herb-disease interaction.


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Pukar Khanal / A Short Introduction on Network Pharmacology: Overview on Bioactives-Targets-Pathways Interaction. Indian Journal of Diabetes and Endocrinology. 2020;2(2):79-81


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Keywords

Geneontology; Network pharmacology; System biology

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