Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

A Randomized Clinical Trial to Compare the Efficacy of Dexmedetomedine and Magnesium Sulphate for Attenuation of Pressor Response in Abdominal Laproscopic Surgeries

Pratibha SD , K. Nirmala Devi1 , Pratibha SD2 , Renuka Holyachi3

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(3):p 749-754, May-June 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6319.8

How Cite This Article:

K. Nirmala Devi, Pratibha SD, Renuka Holyachi. A Randomized Clinical Trial to Compare the Efficacy of Dexmedetomedine and Magnesium Sulphate for Attenuation of Pressor Response in Abdominal Laproscopic Surgeries. Indian J Anesth Analg. 2019;6(3):749-754.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Objectives: To evaluate the response of dexmedetomidine and magnesium sulphate for attenuating stress response in laparoscopic abdominal surgeries. Material and methods: Patients of ASA grade I and II aged between 20 and 60 years, either gender and who underwent elective laparoscopic abdominal surgeries were included in the study and divided into two groups, group D (n=52) and group M (n=52). Group D patients received Inj dexmedetomidine 1 µg/kg bolus for 15 min followed by 0.2-0.4 µg/kg /hr infusion and group M patients received inj magnesium sulphate 2g bolus for 15 min followed by 12-15 mg/kg/hr infusion. Intraoperative hemodynamic parameters like Heart rate, mean arterial pressure were recorded and emergence time, extubation time and sedation scores were assessed. Results: Heart rate and Mean arterial pressure were significantly low in group D compared to group M. Recovery time and sedation score was significantly higher in group M compared to group D. Time to reach Aldrete score ≥ 9 was significantly more in group M compared to group D. Conclusion: Dexmedetomidine and Magnesium sulphate attenuated stress response to surgery and pneumoperitoneum. Dexmedetomidine had better hemodynamic stability compared to Magnesium sulphate. Early post operative recovery was found in dexmedetomidine group.

References

No records found.


About this article

Cite this article

K. Nirmala Devi, Pratibha SD, Renuka Holyachi. A Randomized Clinical Trial to Compare the Efficacy of Dexmedetomedine and Magnesium Sulphate for Attenuation of Pressor Response in Abdominal Laproscopic Surgeries. Indian J Anesth Analg. 2019;6(3):749-754.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6319.8

Keywords

Stress response; laparoscopic surgery; dexmedetomidine; magnesium sulphate.

Article Level Metrics

Last Updated

Monday 13 July 2026, 15:16:04 (IST)

5656

Accesses

5
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share