Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

A Prospective Randomized Double Blind Study for Comparative Evaluation of Bupivacaine with Two Different Doses of Clonidine for Pediatric Caudal Analgesia in Infra Umbilical Surgeries

Panwar Dinesh* , Panwar Dinesh* , Sabharwal Nikki** , Sahni Amita*** , Diwan Sahil*

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 3(2):p 83-91, May-Aug 2016. | DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.3216.3

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

 Introduction: We designed a double blind randomized controlled trial to comparatively evaluate the efficacy of bupivacaine with two different doses of clonidine for pediatric caudal analgesia in infra umbilical surgeries. Methodology: 90 children, 2­10 years of age, weight < 20 kg of either sex, belonging to ASA grade I and scheduled for infra umbilical surgeries were taken up for the study. Patients were divided randomly into three groups of 30 each using the computer generated technique­ Group 1­ 0.75 ml/ kg of 0.25% bupivacaine and 1µg/ kg of clonidine; Group 2 ­ 0.75 ml/kg of 0.25% bupivacaine and 2µg/ kg of clonidine. Group 3: 0.75 ml/ kg of 0.25% bupivacaine. 0.75 ml/ kg of the study drug solution was injected after administration of anaesthesia. Post operative monitoring for heart rate, blood pressure, respiratory rate, SpO2; Post operative analgesia­ using Modified Objective Pain Score. Post operative sedation score using the Four Point Sedation Score was done at the interval of 0, ½, 1, 2,4,8,12,24 hours. results: Efficacy of Post operative analgesia assessed by MOPS score was found to be better in group 2 followed by group 1 and least in group 3. Also, post operative sedation score was highest in Group 2 as compared to group 1 & 3. Conclusion: We recommend a dose of 1µg/kg clonidine as an adjuvant to 0.25% bupivacaine (0.75ml/kg) for infra­umbilical surgeries to significantly prolong post­operative analgesia without causing significant sedation. Increasing the dose of clonidine to 2µg/kg didn’t significantly prolong postoperative analgesia but did produce significant sedation, which might interfere with discharge criteria for day care surgery. 

Keywords: Pediatric Caudal Analgesia; Infra Umbilical Surgeries; Clonidine; Bupivacaine.

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.3216.3

Keywords


Article Level Metrics

Last Updated

Saturday 07 February 2026, 21:06:08 (IST)

1189

Accesses

1
194
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share