Abstract

Background: With the rising prevalence of acute and chronic lung diseases, the onlywaytocompensateforthelossoforganfunctionistouseanarti𿿿cialorganor a transplant. Lung transplantation, on the other hand, is only available to a small percentage of patients due to the scarcity of transplantable organs.Despite the fact thattheorganisarti𿿿ciallyreplacedforthekidneyandheart,ithasbeenafeasible optionformanyyears, arti𿿿cialpulmonarysystemscanonlybereplacedfora short period of time. Aim: To discuss the implications of bio-engineering technologies in inventing the bio-arti𿿿ciallungs. Objectives: To discuss the current barriers to lung transplant in a country like India and discuss the current available treatment options. Results: Longer-lasting wearable systems are now largely owing to advancements intheengineeringofhollow𿿿bermembranegasexchangers,whichcanbeusedto help patients transition from lung failure to transplantation. Conclusion: Advances in the conception of microchannel-based devices, which may even allow intracorporeal implantation, have given rise to the concept of biomimetic devices. Tissue engineering and cell-based technologies have been usedtocreatebioarti𿿿cial lungswithpropertiesthataresimilar tothoseof the natural organs.

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Funding