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A Comparative Study of the Effect of 0.5% Hyperbaric Bupivacaine and 0.5% Isobaric Levobupivacaine on Spinal Anaesthesia in Patients Scheduled for Lower Abdominal Surgeries

Deepa David, Assistant Professor, Dept. of Anaesthesiology, Government Stanley Medical College and Hospital, Chennai, Tamil Nadu 600001, India. , V. Shanmugapriya1 , Deepa David2 , Anandhakumar G.3 , N. Anuradha4

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Indian Journal of Anesthesia and Analgesia 5(8):p 1382-1389, August 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5818.21

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Abstract

Introduction: Recent advances in pharmacology introduced newer local anaesthestic drugs which can be used in subarachnoid block with less motor blockade and less effect on bladder had changed the patient care from prolonged hospital stay to day care.

Aim: This study is to compare the efficacy of 0.5% hyperbaric Bupivacaine and 0.5% isobaric Levo-bupivacaine on spinal anaesthesia, in patients scheduled for Lower Abdominal Surgeries.

Materials and Methods: The study is a randomized control study, including 2 groups of 40 patients each group B and L. group B studied with 3ml of 0.5% hyperbaric bupivacaine, group L studied with 3ml of levo bupivacaine.

Results: Levobupivacaine has more delayed onset of both sensory and motor blockade with more time taken to attain maximum sensory level and faster two segment regression and lesser duration of both sensory and motor block when compared with the bupivacine when the hemodynamic parameters were compared with the two groups, the decrease in HR < 20% of the baseline was not significant in both groups. The decrease in SBP <20% of base line  5/40, levo bupivacaine no fall in SBP/DBP. Adverse effects like bradycardia, shivering, vomiting was not seen in the two groups when compared.

Conclusion: Levobupivacaine has more hemodynamic stability, delayed onset of action and shorter duration of anesthesia than 0.5% Hyperbaric Bupivacaine with comparable duration of motor blockade.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5818.21

Keywords

Spinal Anaesthesia; Levobupivacaine; Bupivacaine; Sensory Blockade; Motorblockade; Hemodynamics.

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