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Indian Journal of Anesthesia and Analgesia

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A Comparative Study of Hyperbaric Bupivacaine 0.5% Versus Hyperbaric Bupivacaine 0.5% with Buprenorphine in Spinal Anesthesia for Lower Abdominal and Lower Extremity Surgeries

Dheeraj R. Patel* , Dheeraj R. Patel* , Naveen Kumar C.P.*

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Indian Journal of Anesthesia and Analgesia 4(2):p 197-201, April - June 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.3

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Abstract

 Background and Objectives: The study was conducted to compare the differences in onset, duration of analgesia of intrathecal hyperbaric bupivacaine 0.5% (Group­I) versus intrathecal hyperbaric bupivacaine 0.5% with buprenorphine 3 mg/kg (Group­II) in spinal anesthesia for lower abdominal and lower extremity surgeries. The combination of bupivacaine and buprenorphine helps anesthesiologist to prolong duration of analgesia without significant side effects. Materials and Methods: The study was prospective, randomized and double blinded. It involved 100 patients (50 per group) of ASA­I and II, aged 18­60 years undergoing lower abdominal and lower extremity surgeries under spinal anesthesia. The time of onset of sensory and motor block, duration of sensory and motor block, hemodynamic stability, visual analogue scale and postoperative analgesia were assessed. Results: The onset of sensory and motor blockade was significantly faster in group­II compared to group­I . The two­segment regression of sensory level and time to complete sensory recovery were significantly longer in group­II. The duration of analgesia was significantly prolonged in group­ II compared to group­I, Patients treated with intrathecal buprenorphine had a better pain relief as judged by visual analogue scale postoperatively. Adverse effects were minimal and easily treatable. Conclusion: Addition of intrathecal buprenorphine 3 mg/kg to hyperbaric bupivacaine 0.5% in spinal anesthesia provides better quality of anesthesia with hemodynamic stability and prolonged duration of analgesia postoperatively without significant side effects.

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DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.3

Keywords

Intrathecal Buprenorphine; Intrathecal Bupivacaine; Post Operative Analgesia; Visual Analogue Scale.

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