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A Comparative Study of 0.5% Levobupivacaine with Dexmedetomidine 50 MCG and 0.5% Levobupivacaine Plain in Supraclavicular Brachial Plexus Block

N. Anuradha, Senior Assistant Professor, Department of Anaesthesiology, Stanley Medical College, Chennai, Tamil Nadu 600001, India. , G. Anandhakumar1 , N. Anuradha2 , Shanmugapriya1 , Deepa David2

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Indian Journal of Anesthesia and Analgesia 4(4):p 992-998, October-December 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4417.13

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Abstract

Context: Several adjuncts are added to local anaesthetic agents to prolong the duration of regional blockade. In this study, we added dexmedetomidine to levobupivacaine for supraclavicular brachial plexus blocks. Aim: To compare the effectiveness of 50 mcg dexmedetomidine added to 0.5% levobupivacaine in supraclavicular brachial plexus block for upper limb surgeries with respect to onset and duration of motor and sensory blockade. Settings and Design: We conducted a randomized double blinded controlled trial on 40 patients, undergoing supraclavicular block. Methods and Material: Group A (n=20) received 30 ml of 0.5% levobupivacaine with 0.5 ml of normal saline and Group B (n=20) received 30 ml of 0.5% levobupivacaine with 0.5 ml of dexmedetomidine (50mcgs/0.5ml). Time of onset, completion and duration were noted for both sensory and motor blockade. Statistical Analysis Used: Chisquare test and student ttest and p value <0.05 was considered as significant. Results: Onset of motor and sensory blockade was significantly shorter with Group B (0.5% levobupivacaine with dexmedetomidine). The mean duration of sensory and motor blockade was significantly prolonged with 591± 30min. and 543±32min respectively. The mean sedation score was 2.60±0.503 (patients were sedated and arousable to verbal or mild physical stimulus) in Group B whereas the score was 1 (fully awake) in Group A. All patients were hemodynamically stable. Conclusion: We conclude that addition of dexmedetomidine 50mcgs to 0.5% levobupivacaine fastens the onset and prolongs the duration of motor and sensory blockade and provides good intraoperative sedation

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4417.13

Keywords

Supraclavicular Brachial Plexus Block; Levobupivacaine; Dexmedetomidine; Nerve Locator. 

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