Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

A Comparative Evaluation of Thiopentone Sodium and Propofol as Inducing Agent for Caesarean Section

Ajai Vikram Singh, Associate Professor, Department of Anaesthesia, Veer Chandra Singh Garhwali Government Institute of Medical Science and Research (VCSGGMSRI), Srinagar, Garhwal, Uttarakhand 246174, India. , Ajai Vikram Singh

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 5(11):p 1777-1783, November-December 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.1

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

  The success of anaesthesia in obstetrics depends largely upon surgical demand and materno­foetal well being. Hence the aim of anaesthesia is to provide safety and comfort to the mother, minimal neonatal depression and optimal working condition for the obstetrician. Propofol 2.5 mg/kg was compared with thiopentone sodium 5mg/kg as induction agent for elective caesarean section. A total of 90 healthy pregnant patients of ASA I and II, who were scheduled for elective caesarean section were included in this study and were randomly allocated into 3 groups. Group I­ Thiopentone sodium 2.5% (5mg/kg), group II­ Propofol 0.5% (2 mg/kg) and group III­ Propofol 1% (2mg/kg). Induction was smooth and rapid with both Propofol and Thiopentone with minimal incidence of side effects. Induction time was found to be shortest with Propofol 1% (40.1±6.11 seconds) as compared to Thiopentone sodium 2.5% (47.2±7.26 seconds) and Propofol 0.5% (70.5±19.58 seconds). Mean arterial pressure was lower in Propofol 1% group during the induction and intra­operatively. Other hemodynamic changes were similar in all three groups. Apnoea occurred less frequently with Propofol 1% (10%) than with Thiopentone sodium (43.33%). Pain on injection (6.66%) and awareness (10%) was found with Propofol whereas cough (3.33%), hiccup (6.66%) and nausea & vomiting (33.33%) were observed with Thiopentone sodium. Recovery time was shorter with clear headedness with Propofol. There was no significant neonatal depression as assessed by Apgar score. Propofol appears to be a better alternative to Thiopentone sodium as induction agent for caesarean section.

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.51118.1

Keywords

General Anaesthesia; Caesarean Section; Propofol; Thiopentone Sodium; Apgar Score

Article Level Metrics

Last Updated

Monday 13 July 2026, 05:06:43 (IST)

5647

Accesses

4
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share