Journal of Microbiology and Related Research

Low level laser therapy helps in various aspects of wound healing. It has effect on cell proliferation, metabolism, angiogenesis, apoptosis and inflammation. This study assess the role of Low level laser therapy (Low Level Laser Therapy) in adult burns patients

Burn patients are prone to sepsis mainly due to the loss of the skin barrier and immunosuppression. Burn wound infections may originate from the patient's endogenous skin, gastrointestinal, and respiratory flora or may be transferred through contact with contaminated external surfaces and infected hands of healthcare workers. Burn patients are vulnerable to infections, especially infections with multidrug resistant organisms which are usually healthcare associated. Healthcare associated infections refer to infections affecting patients in a hospital or other healthcare facility that were not present or incubating at admission. These include occupational infections among healthcare workers and infections acquired in the hospital or other healthcare facilities but appearing after discharge. This study highlights the role of Acineto bacter baumanii as the cause of septicemia in burns.

Pseudomonas aeruginosa is a notorious, opportunistic pathogen and has ability of biofilm formation making it possible to survive in extreme conditions. As antibiotics and disinfectants have shown limited activity, P. aeruginosa phage based treatments are proposed as a promising way for biofilm control. P. aeruginosa isolates and PB1 like phage particles were isolated from sewage samples collected from sewage treatment plants. PB1 like phage was featured with large burst size of 151PFU/cell, host inactivation in 6 hrs, 80% of host range and had icosahedral head with a diameter of 85X80nm and long non contractile tail of 135nm. PB1 like phages are suitable for lysis of broad range MDR Pseudomonas biofilms, which could be used in phage therapy.