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To Evaluate Hemodynamic Effect of Propofol and Etomidate as Induction Agents in Elective Surgeries

Manisha Bhatt Dwivedi, Professor,Department of Anaesthesia, Maharishi Markandeshwar Institute of Medical Sciences and Research (MMIMSR), Mullana, Ambala, Haryana 133207, India. , Babita Ramdev1 , Manisha Bhatt Dwivedi2 , Harinder Singh3

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Indian Journal of Anesthesia and Analgesia 5(4):p 540-544, April 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.6

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Abstract

Introduction: One of the major concerns of the anaesthetist during induction of anesthesia is maintenance of haemodynamic stability. Various induction agents have been used during induction like thiopentone, propofol, ketamine and etomidate.

Aim: The aim of this study was to evaluate the hemodynamic effect ofPropofoland Etomidate as induction agents in elective surgeries undergeneral anesthesia.

Material and Methodology: Sixty (60) patients of age group (1860 years) of ASA grade I and II were randomly divided into two groups of thirty patients each, as follows:

Group I: Propofol 2 mg/kg was given intravenously as induction agent.

Group II: Etomidate 0.3 mg/kg was given intravenously as induction agent. The various haemodynamic parameters were recorded and compared.

Result: A significant difference inhaemodyanamic parameters seen between both the groups. In group I (Propofol) HR, SBP, DBP, MBP significantly decrease at the time of induction and upto 60 minutes (p<0.05) whereas in group II (Etomidate) lesserfall in hemodynamics parameters seen as compared to group I (p>0.05).

Conclusion: Induction with etomidate is associated with lesser fall in haemodynamic parameters as compared to propofol.

 

 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5418.6

Keywords

Induction; Haemodynamic; Parameters; Propofol; Etomidate. 

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