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RFP Journal of Biochemistry and Biophysics

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Study of Glycosylated Hemoglobin and it’s Relation with Changes in Lipid Profile in Type II Diabetic Patients

Raviraj Rajan Naik, Assistant Processor, Department of Biochemistry, IIMSR Medical College, Warudi, Aurangabad, Maharashtra 431005, India. , Raviraj Naik1 , Sarita Dakhure2

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RFP Journal of Biochemistry and Biophysics 2(2):p 73-76, Jul-Dec 2017. | DOI:

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Abstract

Introduction: Patients with type 2 diabetes (T2DM) have an increased prevalence of dyslipidemia, which contributes to their high risk of cardiovascular diseases (CVDs). Hemoglobin A1c (HbA1c) is widely used as an index of mean glycaemia, a measure of risk for the development of diabetes complications and a measure of the quality of diabetes care. This study is an attempt to determine the correlation between hemoglobin A1c (HbA1c) and serum lipid profile and to evaluate the importance of HbA1c as an indicator of dyslipidemia in patients with T2DM. Study Subjects: 100 non obese, non hypertensive type 2 diabetic patients attending the Diabetic OPD, IIMSR Medical College,Jalna will be enrolled in this study. After obtaining informed consent from patients, detailed history will be taken followed by investigations like fasting and post prandial blood sugar, HbA1c and lipid profile (Cholesterol, Triglycerides, HDL, LDL & VLDL). Material &Methods: Lipid profile and blood glucose levels will be analysed using respective biochemical kits Erba EM 200 automated biochemical analyser in central clinical laboratory, Biochemistry section of IIMSR Medical College, Jalna. Glycosylated Hemoglobin was analysed by using SDA1c Care portable analyser.

Keywords: Glycemic Control; HbA1c; Serum Lipid Profile; Type 2 Diabetes. 

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