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Case Report

Sitagliptin Associated Acute Pancreatitis

Archit Dahiya, Senior Resident, Department of General Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana 124001, India. , Archit Dahiya , Isha Nandal

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Indian Journal of Emergency Medicine 4(3):p 234-236, Jul-Sep, 2018. | DOI: http://dx.doi.org/10.21088/ijem.2395.311X.4318.23

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Abstract

Dipeptidyl peptidase IV (DPP-IV) inhibitors such as sitagliptin prolong the duration of active incretin hormones such as glucagon-like peptide 1 (GLP-1) in the bloodstream and thereby enhances control of type 2 diabetes. Adverse events with sitagliptin include upper respiratory tract infections, sore throat, headache and diarrhea. It has also been linked with pan creatitis in case reports, animal studies and postmarketing drug surveillance studies. We report a case of 52 year old diabetic female taking sitagliptin since 2 months presented with abdominal pain and vomiting since 2 days and was diagnosed as acute pancreatitis.
 

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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.4318.23

Keywords

Type II Diabetes Mellitus; Sitagliptin; Dipeptidyl Peptidase Iv Inhibitor; Acute Pancreatitis.

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