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Role of Topical Onion Extract in Scar Management

Ravi Kumar Chittoria, Marenika null, Jacob Antony Chakiath

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International Physiology 10(2):p 53-57, May-August 2022. | DOI: https://doi.org/10.21088/ip.2347.1506.10222.5

How Cite This Article:

Marenika, Ravi Kumar Chittoria, Jacob Antony Chakiath/Role of Topical Onion Extract in Scar Management/International Physiology.2022;10(2):53–57

Timeline

Received : May 30, 2022         Accepted : June 02, 2022          Published : August 25, 2022

Abstract

An imbalance of collagen synthesis and degradation is the most common cause of scarring. Onion extract inhibits fibroblast activity, which helps to reduce scar formation. Despite the fact that onion extract is used in a variety of commercial products, the precise molecular mechanisms by which onion extract reduces scar development in the skin are yet unknown. The aim of this study is to evaluate the effectiveness of onion extract gel in improving the scar.


References

  • 1.   Chanprapaph, K., Tanrattanakorn, S., Wattanakrai, P., Wongkitisophon, P., & Vachiramon, V. (2012). Effectiveness of Onion Extract Gel on Surgical Scars in Asians. Dermatology Research and Practice, 2012.
  • 2.   Jackson, B. A., & Shelton, A. J. (1999). Pilot Study Evaluating Topical Onion Extract as Treatment for Postsurgical Scars. Dermatologic Surgery, 25(4), 267–269.
  • 3.   Campanati, A., Savelli, A., Sandroni, L., Marconi, B., Giuliano, A., Giuliodori, K., Ganzetti & Offidani, A. (2010). Effect of Allium Cepa-AllantoinPentaglycan Gel on Skin Hypertrophic Scars: Clinical and Video-Capillaroscopic Results of an Open-Label, Controlled, Nonrandomized Clinical Trial. Dermatologic Surgery, 36(9), 1439–1444.
  • 4.   Rabello, F. B., Souza, C. D., & Farina, J. A. (2014). Update on hypertrophic scar treatment. Clinics, 69(8), 565.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Marenika, Ravi Kumar Chittoria, Jacob Antony Chakiath/Role of Topical Onion Extract in Scar Management/International Physiology.2022;10(2):53–57


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
May 30, 2022 June 02, 2022 August 25, 2022

DOI: https://doi.org/10.21088/ip.2347.1506.10222.5

Keywords

Scar reductionOnion extract gel

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Received May 30, 2022
Accepted June 02, 2022
Published August 25, 2022

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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