Full Text (PDF)
International Physiology 10(2):p 61-65, May-August 2022. | DOI: https://doi.org/10.21088/ip.2347.1506.10222.6
Original Article
Reconstruction of Amputated Stump with SVC Thrombosis: Our Experience
Ravi Kumar Chittoria, Surya K, Neljo Thomas
Author Information
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
International Physiology 10(2):p 61-65, May-August 2022. | DOI: https://doi.org/10.21088/ip.2347.1506.10222.6
How Cite This Article:
Surya K, Ravi Kumar Chittoria, Neljo Thomas/Reconstruction of Amputated Stump with SVC Thrombosis: Our Experience/ International Physiology.2022;10(2):61–65.Timeline
Received : June 10, 2022
Accepted : July 12, 2022
Published : August 25, 2022
Abstract
Wound healing is an array of planned steps in a sequence which includes inflammation, proliferation and remodelling. Wound healing depends on growth factors, cytokines, interleukins, etc. There is no well-established method that accelerates wound healing. In this article we report how we have managed a case of post traumatic amputation stump who had developed iatrogenic SVC thrombosis, using different regenerative methods like the autologous platelet rich plasma, insulin therapy, prolotherapy, low level laser therapy for augmenting in wound healing. We also successfully managed SVC thrombosis during the hospital course. In this article we also discuss about the role of prolotherapy in wound healing.
References
- 1. Oh JY, Choi GE, Lee HJ. High-glucose-induced reactive oxygen species stimulates human mesenchymal stem cell migration through snail and EZH2-dependent E-cadherin repression. Cell Physiol Biochem. 2018;46:1749–1767.
- 2. Penn JW, Grobbelaar AO, Rolfe KJ. The role of the TGF-β family in wound healing, burns and scarring: a review. Int J Burns Trauma. 2012;2:18–28
- 3. Freeman JW, Empson YM, Ekwueme EC, Paynter DM, Brolinson PG. Effect of prolotherapy on cellular proliferation and collagen deposition in MC3T3-E1 and patellar tendon fibroblast populations. Transl Res. 2011;158:132–139.
- 4. Wu TJ, Fong YC, Lin CY, Huang YL, Tang CH. Glucose enhances aggre can expression in chondrocytes via the PK Calpha/p38-miR141–3p signalling pathway. J Cell Physiol. 2018;233:6878– 6887.
- 5. Topol GA, Podesta LA, Reeves KD. Chondrogenic effect of intra-articular hypertonicdextrose (Prolotherapy) in severe knee osteoarthritis. PMR. 2016;8:1072–1082
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Surya K, Ravi Kumar Chittoria, Neljo Thomas/Reconstruction of Amputated Stump with SVC Thrombosis: Our Experience/ International Physiology.2022;10(2):61–65.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| June 10, 2022 | July 12, 2022 | August 25, 2022 |
DOI: https://doi.org/10.21088/ip.2347.1506.10222.6
Keywords
amputated stumpprolotherapySVC thrombosiswound healingSearch for Similar Articles
Similar Articles
- Role of Topical Onion Extract in Scar Management
- Role of Video Dermatoscopy in Scar Management
- Mechanisms of Myocardial Damage and Structural Remodeling Caused by Doxorubicin-...
- Impact of Sleep Deprivation on Human Physiology: A Review
- The Effect of a Brief Heart Rate Variability Biofeedback Session on Salivary Cor...
Article Level Metrics
Last UpdatedFriday 23 October 2026, 13:51:49 (IST)
2225
Accesses
9
204
00
Citations
NA
NA
NA
Download citation
Article Keywords
Keyword Highlighting
Highlight selected keywords in the article text.
Timeline
| Received | June 10, 2022 |
| Accepted | July 12, 2022 |
| Published | August 25, 2022 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
