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Role of Combination of Autologous Platelet-Rich Plasma and Other Modalities of Adjuvant Therapy in Wound Bed Preparation in Diabetic Foot Ulcer

Ravi Kumar Chittoria, Karthikeyan null, Aayushree Bhagat

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New Indian Journal of Surgery 17(3):p 93-101, July - Sept. 2026. | DOI: 10.21088/nijs.0976.4747.17326.1

How Cite This Article:

Karthikeyan, Aayushree Bhagat, Ravi Kumar Chittoria. Role of Combination of Autologous Platelet Rich Plasma and Other Modalities of Adjuvant Therapy in Wound Bed Preparation in Diabetic Foot Ulcer. New Indian J Surg. 2026; 17(3): 93-101.

Timeline

Received : May 20, 2026         Accepted : June 21, 2026          Published : September 30, 2026

Abstract

Diabetic foot ulcer is one of the common conditions faced by surgeons. A multidisciplinary team approach is mandatory for successful treatment of the condition. Its complexity is mainly due to the involvement of multiple organs and systems. Hence the condition is often found to be difficult to manage. The general concept is that appropriate and timely healing of the wound can prevent various wound-related complications like gangrene, auto amputations, septicemia, multiorgan failure, disfigurement, deformities etc. Adjuvant therapy not only increases wound healing but also can reduce the requirement of graft/flap by reducing the size of the defect and prevent the incidence of various complications like gangrene, amputation. Through this article we present use of Autologous Platelet Rich Plasma (APRP) therapy combined with other modalities of therapy like external tissue expansion and wound closure (ETEWC) technique using hooks and rubber bands as an effective tool to enhance healing in wound bed preparation of diabetic foot.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Karthikeyan, Aayushree Bhagat, Ravi Kumar Chittoria. Role of Combination of Autologous Platelet Rich Plasma and Other Modalities of Adjuvant Therapy in Wound Bed Preparation in Diabetic Foot Ulcer. New Indian J Surg. 2026; 17(3): 93-101.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
May 20, 2026 June 21, 2026 September 30, 2026

DOI: 10.21088/nijs.0976.4747.17326.1

Keywords

Autologous Platelet rich plasmaWound bed preparationDiabetic foot ulcer

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Received May 20, 2026
Accepted June 21, 2026
Published September 30, 2026

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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