Home > Journals > New Indian Journal of Surgery

New Indian Journal of Surgery

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Prophylactic Antibiotics and Surgical Site Infections: the Myths and the Realities

Anil Raj D , Anil Raj D1 , Sreejith PS2

Author Information

Licence:



New Indian Journal of Surgery 12(3):p 147-151, July-September 2021. | DOI: https://dx.doi.org/10.21088/nijs.0976.4747.12321.4

How Cite This Article:

Anil Raj D, Sreejith PS/Prophylactic Antibiotics and Surgical Site Infections: The Myths and the Realities/New Indian J Surg. 2021;12(3):147–151.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: Postoperative wound infections have an enormous impact on patient’s quality of life and contribute substantially to the financial cost of patient care. The potential consequences for patients range from increased pain and care of an open wound to sepsis and even death. Wound infections extend the average hospital stay by one week and increasing the cost of hospitalization by minimum of 20%. Appropriate antibiotics for prophylaxis in surgery depend on the most likely pathogens encountered during the surgical procedure and type of operative wound encountered during the surgical procedure. Inadvertent use of antibiotics is associated with Development of multi-agent drug resistance among nosocomial pathogens. The occurrence of new infections such as clostridium difficile colitis, respiratory tract infections Drug toxicity and allergy Enormous financial impact on health care costs. Objective: To know whether prophylactic dose of antibiotics is enough to prevent surgical siteinfections in post-operative period if there is no comorbidities and surgery is donewith complete aseptic precautions. Methodology: The patients who undergoes clean and clean contaminated surgeries in PK Das Institute of Medical Sciences, Vaniamkulam, Palakkad, Kerala over period of 2 years and who fulfill the criteria of study aredivided randomly into two different groups (70 cases and 70 controls). Routineinvestigations done in both groups. And all other parameters are kept similar like preoppreperations and intra-op strategies. Case group received only prophylacticantibiotic and control group received post-operative empirical antibiotics also. 70patients in case group contain 35 clean cases and 35 clean contaminated cases. 70patients in control group also divided like this. Results: Out of the 35 clean cases in study group 3 got SSI. Out of 35 clean contaminated cases in study group 7 got SSI Out of 35 clean cases in control group 4 got SSI Out of 35 clean contaminated cases in control group 8 got SSI Conclusion: The use of prophylactic antibiotics alone is as effective as post-op empirical therapy in preventing SSI. This will also avoid unnecessary antibiotic resistance and will reduce the cost of treatment.

Keywords: Prophylactic; Empiric therapy; Wound Infections; Antibiotic resistance.

References

No records found.


About this article

Cite this article

Anil Raj D, Sreejith PS/Prophylactic Antibiotics and Surgical Site Infections: The Myths and the Realities/New Indian J Surg. 2021;12(3):147–151.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: https://dx.doi.org/10.21088/nijs.0976.4747.12321.4

Keywords


Article Level Metrics

Last Updated

Saturday 28 February 2026, 19:50:48 (IST)

507

Accesses

0
158
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share