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Indian Journal of Obstetrics and Gynecology 13(3):p 119-124, July - Sept. 2025. | DOI: ijog.2321.1636.13325.5
Case Report
Ovarian Carcinoma with Two Discrete Histologies: The Rarest of Rare
Sushmita, , Pavika Lal, Garima Gupta, Renu Gupta, Chayanika Kala
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Obstetrics and Gynecology 13(3):p 119-124, July - Sept. 2025. | DOI: ijog.2321.1636.13325.5
How Cite This Article:
Lal P, Gupta G, Gupta R, et al. Ovarian Carcinoma with Two Discrete Histologies: The Rarest of Rare. Indian J Obstet Gynecol. 2025;13(3):119-24.Timeline
Received : April 18, 2025
Accepted : June 05, 2025
Published : September 30, 2025
Abstract
A 46-year-old postmenopausal woman presented with abdominal lump, weight loss, anorexia, and dyspepsia. Imaging revealed bilateral ovarian masses, and she underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathological examination revealed a rare case of bilateral primary ovarian cancer with two distinct histopathologies: high-grade serous carcinoma in the left ovary and endometrioid carcinoma in the right ovary. The patient had a history of breast cancer and was suspected to have a genetic predisposition, but genetic screening was declined due to economic constraints. The case highlights the rarity of synchronous bilateral primary ovarian cancers and the importance of meticulous histopathological evaluation and multidisciplinary collaboration in management. The patient was referred for adjuvant treatment, and the case underscores the need for further research and personalized treatment approaches for such complex ovarian malignancies.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work
About this article
Cite this article
Lal P, Gupta G, Gupta R, et al. Ovarian Carcinoma with Two Discrete Histologies: The Rarest of Rare. Indian J Obstet Gynecol. 2025;13(3):119-24.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 18, 2025 | June 05, 2025 | September 30, 2025 |
DOI: ijog.2321.1636.13325.5
Keywords
Synchronous Bilateral Ovarian CancerEndometroid CarcinomaHigh Grade Serous CarcinomaSearch for Similar Articles
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Timeline
| Received | April 18, 2025 |
| Accepted | June 05, 2025 |
| Published | September 30, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
