Abstract

Male infertility, a complex condition affecting a significant proportion of couples worldwide, often involves genetic factors such as Y chromosome microdeletion, mutations in Azoospermia factor (AZF) genes, SRY gene, and Androgen receptor (AR) gene. These genetic abnormalities can lead to impaired spermatogenesis and resultant azoospermia or oligospermia. Understanding these genetic factors is crucial for diagnosis and management of male infertility. Yoga-based alternative therapies have gained attention for their potential in improving overall health and well-being, including reproductive health. Studies have suggested that yoga practices, encompassing physical postures (asanas), breathing techniques (pranayama), and meditation, can reduce stress, enhance hormonal balance, improve blood circulation, and modulate immune function. These benefits may contribute to ameliorating underlying causes of male infertility associated with genetic mutations. This review explores the role of Y chromosome microdeletion, AZF gene mutation, SRY gene mutation, and AR gene mutation in male infertility and reviews the potential of yoga-based alternative therapies in mitigating these genetic factors. Further research and clinical trials are warranted to validate the efficacy of yoga as a complementary approach to conventional treatments for male infertility.

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