Full Text (PDF)
Indian Journal of Emergency Medicine 10(2):p 85-89, Aril-June 2024. | DOI: https://doi.org/10.21088/ijem.2395.311X.10224.9
Case Report
Lactic Acidosis: A Diagnostic Conundrum
Anjali P. U, Jerry Jacob, Aruna C. Ramesh
Author Information
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Emergency Medicine 10(2):p 85-89, Aril-June 2024. | DOI: https://doi.org/10.21088/ijem.2395.311X.10224.9
How Cite This Article:
PU A, Jacob J, Ramesh AC. Lactic acidosis: a diagnostic conundrum. Ind J Emerg Med. 2024;10(2):85-9.Timeline
Received : April 03, 2024
Accepted : May 22, 2024
Published : June 04, 2024
Abstract
Lactic acidosis is due to increased serum lactate (>5.0mmol/L) leading to decrease in blood pH. Alcoholic keto-acidosis is one of the several etiologies where serum lactate level rarely exceeds 3mmol/L. Here we present a case of 59yr old male presented to ED with c/o abdominal pain and multiple episodes of vomiting following consumption of alcohol. On examination, patient was tachypneic, tachycardic with BP of 90/60mmHg. Arterial blood gas showed severe metabolic acidosis with a pH of 6.96, pCO2 of 21.4, pO2 of 57.1, HCO3 of 4.7 and Lactate of 14.48. On probing history, attenders revealed consumption of illicit liquor by patient on previous night giving rise to suspicion of methanol toxicity.
References
- 1. Qiuying SL, Farzana Hetal,Type B lacticacido sis: arareoncologicalemergency BMJ Case Rep 2020; 13(3):e233068.
- 2. FoucherCD, TubbenRE .LacticAcidosis. [Updated2023Jul17] .In:StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.
- 3. Kowlgi NG, Chhabra L. D-lactic acidosis: an underrecognized complication of short bowel syndrome. Gastroenterol Res Pract. 2015;2015:476215. doi: 10.1155/20 15/4762 15.Epub2015Ar22. PMID:25977687;PMCID:PMC4421027.
- 4. Yang CC, Chan KS, Tseng KL, Weng SF. Prognosis of alcohol-associated lactic aci dosisincriticallyillpatients:an8-yearstudy. SciRep.2016Oct17;6:35368.doi:10.1038/ srep35368. PMID: 27748410; PMCID: PMC5066311.
- 5. McGuire LC, Cruickshank AM, Munro PT. Alcoholic ketoacidosis. Emerg Med J. 2006Jun;23(6):417-20.doi>10.1136/ emj.2004.017590.PMID:16714496;PMCID: PMC2564331.
- 6. Adarsha Ojhaand Luna Khanal: Severel acticacidos is secondary to acute alcohol into!ication. Americal Iournal of chest physician 2021.07.781.
- 7. Chen Y, Du Y, Sun C, Tan W. Lactate is Associated with Increased 30-Day Mortalityin CriticallyIll Patients with Alcohol Use Disorder. Int J Gen Med.2021 Jun 23;14:2741-2749. doi: 10.2147/IJGM.S314821. PMID: 34194237; PMCID: PMC8236836.
- 8. Stancy Mosel, L.M.S.W, Alcoholicke to acidosis: signs, symptom sand treatment; sep14, 2023.
- 9. Godinjak A, Jusufovic S, Rama A,IglicaA, ZvizdicF, Kukuljac A, TancicaI, Rozajac S. Hyperlactatemia and the Importance of Repeated Lactate MeasurementsinCritically IllPatients.MedArch.2017Dec;71(6):404-407. doi: 10.5455/medarh.2017.71.404-407. PMID: 29416200; PMCID: PMC5770196.
- 10. MdNoor, J., Hawari, R., Mokhtar, M.F.etal. Methanoloutbreak:aMalaysian tertiary hospital experience. Int J Emerg Med 13, 6 (2020). https://doi.org/10.1186/s12245-020-0264-5.
- 11. KrautJ.Approachtothetreatmentofmethanolinto xication.AmJKidneyDis. 2016;68(1):1616-7.
- 12. Allata Y, Chouhani B, El Bardai G, et al. (April 12, 2023) The Role of Nephrologist sintheManagementofMethanolPoisoning. Cureus15(4):e37471.
- 13. Kyle J Gunnerson: Lacticacidosis; september 11,2020.
- 14. Abedi E, Hashemi SMB. Lacticacid production producing micro organisms and substrates sources-state of art. Heliyon. 2020 Oct 12;6(10):e04974. doi: 10.1016/j.heliyon.2020. e04974. PMID: 33088933; PMCID: PMC7566098.
- 15. N Zahra, Z Zakariaetal. Methanol poisoiningasa new world challenge: A review; June 2021, 102445.
Data Sharing Statement
There are no additional data available.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Acknowledgements
Information not provided.
Conflicts of Interest
The authors report no conflicts of interest in this work.
About this article
Cite this article
PU A, Jacob J, Ramesh AC. Lactic acidosis: a diagnostic conundrum. Ind J Emerg Med. 2024;10(2):85-9.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 03, 2024 | May 22, 2024 | June 04, 2024 |
DOI: https://doi.org/10.21088/ijem.2395.311X.10224.9
Keywords
Lactic acidosisMethanol intoxicationSearch for Similar Articles
Similar Articles
- Crossroads of Industrial Chemistry and Clinical Toxicology: A Rare Case of Orga...
- A Tale of Double Vision
- Incidental Diagnosis of Graves’ Disease in a Patient Presenting with Influenza:...
- Avulsion Fracture Hidden in X-Ray Detected by Point-of-Care Ultrasound in a Youn...
- Disseminated Deep Neck Space Infection in an Immunocompetent Adult: A Case Repor...
Article Level Metrics
Last UpdatedWednesday 17 June 2026, 16:04:57 (IST)
2147
Accesses
10
735
00
Citations
NA
NA
NA
Download citation
Article Keywords
Keyword Highlighting
Highlight selected keywords in the article text.
Timeline
| Received | April 03, 2024 |
| Accepted | May 22, 2024 |
| Published | June 04, 2024 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
