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HIV/AIDS-associated Peripheral Neuropathy and Neuropathic Pain- a Complication or a Consequence?

*Nisha Rani Jamwal, **Kumar Senthil P. , Kumar Senthil P.

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Indian Journal of Communicable Diseases 1(1):p 29-31, Jan-Jun 2015. | DOI:

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Abstract

This article was aimed to highlight the prevalence, risk factors, clinical presentation, management and self-care strategies for HIV/AIDS-induced neuropathy through an evidence informed overview of literature in PubMed.Studies show relatively higher prevalence rates for peripheral neuropathy ranging from 40-45% among people living with HIV/AIDS (PLWHA), with neuroanatomical changes in axons and myelin sheaths of peripheral sensory nerves, clinical presentation of distal symmetric polyneuropathy scondary to HIV infection and/or due to anti-retroviral therapy induced toxic neuropathy, with lower extremity splinting and various self-reported self-management strategies including application of local moist heat. The study findings are of immense importance to clinicians and researchers working on PLWHA in order to prevent, diagnose and treat HIV/AIDS-related neuropathy, so that multidimensional management could be planned to enhance quality of life of PLWHA.
 
Keywords: Neuroimmunology, Immunoneurology, HIV/AIDS-related neuropathy, HIV/AIDS-related pain.

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