Abstract

Fungal pathogens and infections are an increasing global public health concern. People most at risk are those with underlying health problems or a weakened immune system, such as chronic lung disease, prior tuberculosis (TB), HIV, cancer, and diabetes mellitus. According to researchers over 5.7 crore Indians are affected by serious fungal conditions; around 4.1% of the Indian population is probably affected, which is similar to reports from other countries like China, Brazil, Korea, Senegal, and Germany. Over 300 million people worldwide suffer from major fungal illnesses, which cause 1.6 million deaths yearly. The World Health Organisation Fungal Priority Pathogen List (FPPL) intends to concentrate and direct additional research and policy measures to boost the international response to fungal infections and antifungal resistance.

• 1.   Bongomin, F., Gago, S., Oladele, R. O., & Denning, D. W. (2017). Global and multi-national prevalence of fungal diseases—estimate precision. Journal of fungi, 3(4), 57.
• 2.   Kainz, K., Bauer, M. A., Madeo, F., & CarmonaGutierrez, D. (2020). Fungal infections in humans: the silent crisis. Microbial Cell, 7(6), 143.
• 3.   Nucci, M., & Marr, K. A. (2005). Emerging fungal diseases. Clinical Infectious Diseases, 41(4), 521-526.
• 4.   World Health Organization. 2022. WHO fungal priority pathogens list to guide research, development and public health action. Available at: who. int/publications/i/item/9789240060241
• 5.   Dhillon, P. K., Mathur, P., Nandakumar, A., Fitzmaurice, C., Kumar, G. A., Mehrotra, R.,& Dandona, L. (2018). The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990–2016. The Lancet Oncology, 19(10), 1289-1306.
• 6.   Ray, A., Aayilliath K, A., Banerjee, S., Chakrabarti, A., & Denning, D. W. (2022, December). Burden of serious fungal infections in India. In Open Forum Infectious Diseases (Vol. 9, No. 12, p. ofac603). US: Oxford University Press.
• 7.   Down to earth. Rise of the fungus. 2023. Cover story/ emerging diseases. Down To Earth 1-15 may 2023, Down To Earth.Org. In.30-39
• 8.   Chakraborty, A., Jasieniak, M., Coad, B. R., & Griesser, H. J. (2021). Candida albicans Can Survive Antifungal Surface Coatings on Surfaces Raghupathi Challagurugula, Sanjay Shakya, Anil Patyal et al. Fungal Infections in Humans: An Emerging Threat with Microcone Topography. ACS Applied Bio Materials, 4(11), 7769-7778.
• 9.   Clancy, C. J., & Nguyen, M. H. (2017). Emergence of Candida auris: an international call to arms. Clinical Infectious Diseases, 64(2), 141-143.
• 10.   Rhodes, J., & Fisher, M. C. (2019). Global epidemiology of emerging Candida auris. Current opinion in microbiology, 52, 84-89.
• 11.   Baid, S. 2022. Combatting Antifungal Resistance. American Society for Microbiology journal. https://asm.org/Articles/2022/November/ CombattingAntifungal-Resistance.
• 12.   Chakrabarti, A., & Slavin, M. A. (2011). Endemic fungal infections in the Asia-Pacific region. Medical Mycology, 49(4), 337-344.
• 13.   Denning, D. W., & Chakrabarti, A. (2017). Pulmonary and sinus fungal diseases in nonimmunocompromised patients. The Lancet Infectious Diseases, 17(11), e357-e366.
• 14.   Denning, D. W. (2016). Minimizing fungal disease deaths will allow the UNAIDS target of reducing annual AIDS deaths below 500 000 by 2020 to be realized. Philosophical Transactions of the Royal Society B: Biological Sciences, 371(1709), 20150468.
• 15.   Rodrigues, M. L., & Albuquerque, P. C. (2018). Searching for a change: The need for increased support for public health and research on fungal diseases. PLoS neglected tropical diseases, 12(6), e0006479.
• 16.   Fisher, M. C., Alastruey-Izquierdo, A., Berman, J., Bicanic, T., Bignell, E. M., Bowyer, P., & Verweij, P. E. (2022). Tackling the emerging threat of antifungal resistance to human health. Nature reviews microbiology, 20(9), 557-571.
• 17.   Centers for Disease Control and Prevention. 2022. Think Fungus: Fungal Disease Awareness Week.(https://www.cdc.gov/fungal/pdf/cdcantifungal-resistance-508.pdf).

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