Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Effect of Midazolam Pre-medication on Induction Dose of Propofol in Adult Patients in Elective Surgery

Aher Pranjali Y , Aher Pranjali Y1 , Sangale Swapnil V2 , Subhedhar Rajesh3 , Murugraj Shivkumar4 , Selvarajan N5

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(5):p 1541-1545, September-October 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6519.8

How Cite This Article:

Aher Pranjali Y, Sangale Swapnil V, Subhedhar Rajesh et al. Effect of Midazolam Pre-medication on Induction Dose of Propofol in Adult Patients in Elective Surgery. Indian J Anesth Analg. 2019;6(5 Part-1):1541-1545.

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: The study based on that midazolam pre-medication reduces the induction dose and cost of propofol. Aims: To study effect of midazolam pre-medication on induction dose of propofol in adult patients. Methods: A prospective randomized, double blind control study was conducted. Total 60 patients (16–45 years) were divided into 2 groups. Group 1 received 0.05 mg/kg of Midazolam and Group 2 received Normal Saline. We compared the induction dose of propofol in both groups, taking loss of verbal contact as the end point. Additionally, changes in hemodynamic status like blood pressure and heart rate and induction time were studied and compared in both groups. Results: The dose of Propofol required to induce anesthesia in Midazolam group was 1.32 mg/kg and 2.27 mg/kg in the control group. The hemodynamic changes in Midazolam group compared to NS were non-significant. Conclusion: We recommend midazolam when used in combination with propofol reduces the dose of propofol and the time required for induction.

References

No records found.


About this article

Cite this article

Aher Pranjali Y, Sangale Swapnil V, Subhedhar Rajesh et al. Effect of Midazolam Pre-medication on Induction Dose of Propofol in Adult Patients in Elective Surgery. Indian J Anesth Analg. 2019;6(5 Part-1):1541-1545.

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6519.8

Keywords

Pre-medication; Midazolam; Induction; Propofol.

Article Level Metrics

Last Updated

Monday 13 July 2026, 07:36:34 (IST)

5648

Accesses

3
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share