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DFSP- Study of Cases in Our Hospital

Reina Khadilkar, Associate Professor, Dept. of Surgery, Dr D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra 411018, India. , Anuradha Dnyanmotea , Reina Khadilkarb , Siddharth Khadilkarc

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New Indian Journal of Surgery 9(2):p 213-217, March - April 2018. | DOI: https://dx.doi.org/10.21088/nijs.0976.4747.9218.19

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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing, fibrohistiocytic neoplasm with intermediate-to low-grade malignancy that commonly favors young to middle-aged adults. It is most commonly seen on the trunk followed by the proximal extremities and the head and neck [1,2]. The potential for distant metastasis is low, but DFSP frequently recurs locally after incomplete excision. The general immunostaining pattern of DFSP is CD34 positive and factor XIIIa negative. Mohs micrographic surgery (MMS) is the treatment of choice for DFSP. Presenting a study of five cases of Dermatofibrosarcoma protruberans which were admitted to our hospital during the period of two years from Jan 2015 to December 2016. All five patients presented with large irregular growths over the body, slow-growing and accompanied with itching and bloody discharge. Four out of five were males and one patient was female. All five patients were thoroughly investigated, biopsy proved and then subjected for surgery. Immunological assessment was also done. Wide local excision with skin grafting was done. All had positive histopathology for DFSP. Four out of five patients came back for follow-up on a regular basis and have shown no recurrence. One patient was lost on follow-up.

 

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DOI: https://dx.doi.org/10.21088/nijs.0976.4747.9218.19

Keywords

Dermatofibrosarcoma protruberans; Ulcerated growths; Immunostaining; Wide excision; biopsy

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