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Indian Journal of Maternal-Fetal & Neonatal Medicine 3(1):p 5-8, January-June 2016. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.3116.1
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Comparative Study between Nifedipine and Isoxsuprine for Suppression Preterm Labour
Suhas Shinde* , Suhas Shinde* , Gautam Aher** , Urmila Gavali*
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Indian Journal of Maternal-Fetal & Neonatal Medicine 3(1):p 5-8, January-June 2016. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.3116.1
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Abstract
Objectives: To compare the efficacy and safety of oral nifedipine and parenteral isoxsuprine in suppression of preterm labour. Methods: This is a prospective trial. 100 antenatal cases with 28- 36 weeks of gestation with threatened or early preterm labour were selected and divided in 2 groups. Group A received oral nifedipine, while group B received parenteral isoxsuprine. Outcome was analyzed with respect to prolongation of pregnancy, maternal and fetal side effects. Conclusion: Nifedipine is preferred tocolytic agent than isoxsuprine in arrest of early preterm labour with lesser maternal side effects.
Keywords: Preterm Labour; Nifedipine; Isoxsuprine.
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DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.3116.1
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