Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Comparative Evaluation of Effect, Onset & Duration of Intranasal Dexmedetomidine Vs Midazolam for Paediatric Sedation During Diagnostic CT Scan

Ashwin Sonkamble null, Somiya Gautam 1 null, Ashwin Sonkamble 2 null, Poornima Sonkamble 3 null, Usha Badole 4 null

Author Information

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Indian Journal of Anesthesia and Analgesia 9(3):p 119-123, May-June 2022. | DOI: https://doi.org/10.21088/ijaa.2349.8471.9322.10

How Cite This Article:

Somiya Gautam, Ashwin Sonkamble, Poornima Sonkamble, et al./Comparative Evaluation of Effect, Onset & Duration of Intranasal Dexmedetomidine Vs Midazolam for Paediatrics Sedation During Diagnostic CT Scan/ Indian J Anesth Analg. 2022;9(3)119-123
 

Timeline

Received : April 25, 2022         Accepted : May 26, 2022          Published : June 20, 2022

Abstract

Background: Separation anxiety among children is common and normal.Children undergoing radiological imaging studies often require sedation to avoid panic episodes & severe anxiety for induction of Anaesthesia. It is important for the child to lie still during the scanning procedure & mostly we find it difficult for the children to keep still during a CT scan, which is usually about 10–15 minutes. This study aimed at comparing and evaluating the efficacy of use of intranasally administered Dexmedetomidine Vs intranasal midazolam for paediatric sedation undergoing diagnostic CT scan studies.

Methods: 100 paediatric patients within age group 1-10 years were divided into 2 groups of 50 patients each, Group I & II respectively, were given either intranasal Dexmedetomidine or Intranasal Midazolam. The depth of sedation was assessed by using University of Michigan sedation scale.

Results: This study concluded that Intranasal Dexmedetomidine is superior & more effective than Midazolam for pediatric sedation.

References

  • 1.   Mason KP, Zgleszewski SE, Dearden JL, Dumont RS, Pirich MA, Stark CD, D'Angelo P, Macpherson S, Fontaine PJ, Connor L, Zurakowski D. Dexmedetomidine for pediatric sedation for computed tomography imaging studies. AnesthAnalg. 2006 Jul;103(1):57-62.
  • 2.   Jun JH, Kim KN, Kim JY, Song SM: The effects of intranasal dexmedetomidine premedication in children:a systematic review and metaanalysis;2017Sep;64(9):947-961.doi:10.1007/s12630-017-0917-x.Epub 2017 Jun21.
  • 3.   Akin A, Bayram A, Esmaoglu A, Tosun Z, Aksu R, Altuntas R, Boyaci A: Dexmedetomidinevs midazolam for premedication of pediatric patients undergoing anesthesia; PaediatricAnaesth. 2012 Sep;22(9):871-6. doi: 10.1111/j.1460-9592.2012.03802.x. Epub 2012 Jan23
  • 4.   Pasin L, Febres D, Testa V, Frati E, Borghi G, LandoniG, Zangrillo A: Dexmedetomidinevs midazolam as preanesthetic medication in children: a meta- analysis of randomized controlled trials;PaediatrAnaesth. 2015 May;25(5):468-76. doi: 10.1111/pan.12587. Epub 2015Jan 6.
  • 5.   Dr.Pradipta Bhakta, Dr. B. R. Ghosh, Dr. Manjushree Roy, Dr.Gouri Mukherjee. Evaluation of intranasal
  • 6.   Peng K, Wu SR, Ji FH, Li J. Premedication with dexmedetomidine in pediatric patients: a systematic review and meta-analysis. Clinics. 2014;69(11):777-786.
  • 7.   Talon MD, Woodson LC, Sherwood ER, Aarsland A, McRae L, Benham T. Intranasal dexmedetomidine
  • 8.   Sheta SA, Al-Sarheed MA, Abdelhalim AA. Intranasal dexmedetomidinevs midazolam for premedication in children undergoing complete dental rehabilitation: A double-blinded randomized controlled trial. Paediatric Anaesth 2014;24:181-9.
  • 9.   Malineni N, Patil MC. “Comparative evaluation of intranasal dexmedetomidine and intranasal
  • 10.   Davis PJ, Tome JA, McGowan FX Jr., Cohen IT, Latta K, Felder H. Preanesthetic medication with
  • 11.   Dr. ShwetaNitturi, Dr. OlvynaD’souza. A Comparative Evaluation of Intranasal Dexmedetomidine and Intranasal Midazolam for Premedication in Pediatric Surgery. IAIM, 2018; 5(1): 82-94.
  • 12.   Malviya S, Voepel-Lewis T, Tait AR, Merkel S, Tremper K, Naughton N. Depth of sedation in children undergoing computed tomography: validity and reliability of the University of Michigan Sedation Scale (UMSS).Br J Anaesth. 2002 Feb;88(2):241-5.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

Provide information related to the Ethics Committee approval with approval number OR write, This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.

About this article

Cite this article

Somiya Gautam, Ashwin Sonkamble, Poornima Sonkamble, et al./Comparative Evaluation of Effect, Onset & Duration of Intranasal Dexmedetomidine Vs Midazolam for Paediatrics Sedation During Diagnostic CT Scan/ Indian J Anesth Analg. 2022;9(3)119-123
 

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
April 25, 2022 May 26, 2022 June 20, 2022
DOI: https://doi.org/10.21088/ijaa.2349.8471.9322.10

Keywords

:Intranasal;Dexmedetomidine;Midaolam;Pediatrics;Children;Sedation;CScan

Article Level Metrics

Last Updated

Monday 13 July 2026, 12:32:15 (IST)

5653

Accesses

6
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received April 25, 2022
Accepted May 26, 2022
Published June 20, 2022

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share