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Comparative Evaluation of Clonidine and Nalbuphine for Control of PostSpinal Anaesthesia Shivering

Sandip Baheti , Ashwini Khamborkar , Sandip Baheti , Smurti Govekar

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Indian Journal of Anesthesia and Analgesia 7(1):p 235-240, January-February 2020. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7120.32

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Ashwini Khamborkar, Sandip Baheti, Smurti Govekar. Comparative Evaluation of Clonidine and Nalbuphine for Control of
Post-Spinal Anaesthesia Shivering. Indian J Anesth Analg. 2020;7(1 Part -II):235-240.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

 

The aim of this study was to evaluate the efficacy, potency and side effects of clonidine and nalbuphinen in postspinal anesthesia shivering. In this prospective double-blind randomized controlled clinical trial, 60
American Society of ASA Grade I and II patients aged between 18 and 60 years scheduled for various surgical procedures under spinal anesthesia, who developed shivering were selected. The patients were divided into Two Groups: Group C (n = 30) comprised of patients who received clonidine 1 mcg/kg intravenously (IV) and Group N patients who received nalbuphine 0.05 mg/kg IV. Grade of shivering, disappearance of shivering, hemodynamic and side effects were observed at scheduled intervals. Disappearance of shivering
was significantly earlier in Group C (2.75 ± 1.35) than in Group N (3.58 ± 1.19) (p = 0.01704). Bradycardia is seen more in Group C than Group N (p = < 0.001). Whereas, sedation is seen in Group N after drug administration but patient remain hemodynamically stable in Group N. We conclude that both the drugs are effective but nalbuphine controls shivering with more hemodynamic stability.
 

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Cite this article

 

Ashwini Khamborkar, Sandip Baheti, Smurti Govekar. Comparative Evaluation of Clonidine and Nalbuphine for Control of
Post-Spinal Anaesthesia Shivering. Indian J Anesth Analg. 2020;7(1 Part -II):235-240.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7120.32

Keywords

Spinalanesthesia; Shivering; Clonidine; Nalbuphine.

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