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Indian Journal of Anesthesia and Analgesia 4(1):p 145-148, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4117.24
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Clinical Study on Complications of Ketamine
Leelavathy P.B.* , M. SalimIqbal* , Leelavathy P.B.* , Junaid Ahmed Desai** , K.S. Jyothsna Prabhat**
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Indian Journal of Anesthesia and Analgesia 4(1):p 145-148, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4117.24
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Abstract
Introduction: Intrathecally administered ketamine is advantageous as its beneficial effects on the cardiovascular system and respiratory functions may be combined with the analgesic effects of spinal anesthesia. The primary mechanism of action of the spinal anesthetic ketamine is noncompetitive blocking of the NMDA ionophore. Methodology: 100 Patients were monitored continuously using sphygmomanometer, pulse oximeter and electrocardiogram. After spinal anesthesia the patients pulse rate and blood pressure were recorded at 0, 5, 10, 20, 30, 45, 60, 90 and 120 minutes. Results: The most common complication was nystagmus, which was present in all males and females, followed by sedation, which occurred in 45 males and 25 females. Only 4 patients had delirium reaction. Conclusion: Intrathecal ketamine with adrenaline produces a reliable anesthesia, better operative conditions and patients comfort with minimal side effects.
Keywords: Ketamine; Complications; Blood Pressure.
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DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4117.24
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