Abstract

Dengue infection presents varied clinical manifestation ranging from asymptomatic or simple viral illness to circulatory shock (DSS), severe bleeding and death. So,early diagnosis and recognition of complication is a cornerstone in management. It is prospective observational study which was conducted in KVG medical college. With inclusion of 100 cases all seropositive for dengue antigen or antibodies or both and platelet count less than 1 lakh/cumm. Done from October 2022 till September 2023.Chis quare test was used for data analysis. The study was mainly focused on bleeding manifestations, to find correlation between platelet count and bleeding manifestations. Routine investigations that include CBC with ESR, RUE, ECG, Dengue serology(NS1, igm, igg), RFT,LFT, serum electrolytes. Coagulation profile was done in suspected dhf patients. Leucopoeniais taken below 4000cells/cumm. Out of 100patients, 88 were classified under dengue fever with/without haemorrhage and rest 12 were classified into Dengue haemorrhagic fever as per WHO criteria. The presenting symptoms were: fever (97%),headache (78%), retroor bital pain (32%), myalgia (72%), arthralgia(52%), nausea(62%), Vomiting (39%), abdominal pain (56%), diarrhoea (15.2%), bleeding manifestations (42%). The major physical findings noted included positive tourniquet test (21%), hepatomegaly (15%),bradycardia (18%), pleural effusion (6%) and ascites (11%). The study concluded that there was no association between bleeding manifestation and platelet counties bleeding can happen at any level of plate lets count. Hence prognostication based on platelet count can’t be done.

• 1.   Comprehensive Guideline for Prevention and Control of Dengue and Dengue Haemorrhagic Fever. Revised and expanded edition (2011). WHO Regional Office for South-East Asia.
• 2.   Dengue: guidelines for diagnosis, treatment, prevention and control. Geneva:World Health Organization; 2009.
• 3.   World Health Organization. Guide lines for treatment of dengue fever/dengue haemorrhagic fever in small hospitals. WHO, SEARO, New Delhi, 1999.
• 4.   Sharma S and Sharma SK. Clinical profile of DHF in adults during 1996 outbreak in Delhi, India. Dengue Bulletin. 1998; 22: 20-27.
• 5.   Bhaskar ME, Moorthy S, Kumar NS, Arthur P. Dengue haemorrhagic fever among adults-an observational study in Chennai, south India.Indian J Med Res. 2010 Dec;132(6):738-40.
• 6.   D. Chhina, P. Goyal, O. Goyaletal. A Study of Clinical Profile of Dengue Fever in Punjab, North India. International Journal of Infectious Diseases, 2008-12-01, Volume 12, Pages e98-e98.
• 7.   Daniel R, Rajmohnan, and Philip AZ. A study of clinical profile of dengue fever in Kollam, Kerala, India. Dengue Bulletin. 2005;29.
• 8.   Chhotala, Y. H., & Suva, C. M. (2016). A study of clinical profile of dengue fever in Jamnagar, Gujarat, India. International Journal of Research in Medical Sciences, 4(10),4500-4504.
• 9.   Bhaswati Bandyopadhyay, Indrani Bhattacharyya et al, “A Comprehensive Study on the 2012 Dengue Fever Out break in Kolkata, India”, International Scholarly Research Notices, vol.2013,Article ID 207580, 5 pages, 2013.
• 10.   Yizhao Lang; Dengue fever; from Wikipedia, the free encyclopedia; August 24, 2009;1-3. http://en.wikipedia.org/wiki/Dengue_fever.
• 11.   Kularatne, Senanayake A M. “Dengue fever.” BMJ :British Medical Journal 2015) 351): n.pag.
• 12.   “Dengue and severe dengue Fact sheet N°117”. WHO. May 2015.

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