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Clinical Evaluation of Katupila Nirudhhalepa in Management of Dusta Vrana

Snehal R. Sonani, PhD Scholar, Snehal R Sonani1 null, Vivekanand Kullolli2 null, Shailesh Jaiswal3 null, Krishna Thorat4 null

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Indian Journal of Ancient Medicine and Yoga 15(4):p 141-148, October – December 2022. | DOI: https://doi.org/10.21088/ijamy.0974.6986.15422.2

How Cite This Article:

Snehal R Sonani, Vivekanand Kullolli, Shailesh Jaiswal, et. al./Clinical Evaluation of Katupila Nirudhhalepa in Management
of Dusta Vrana/Indian J of Ancient & Yoga. 2022;15(4): 141–148.

Timeline

Received : October 01, 2022         Accepted : October 29, 2022          Published : November 30, 2022

Abstract

Context: Dustavraa is a combination of two Sanskrit words meaning Dusta as contaminated/ infected/chronic/non-healing and Vrana as Ulcer/wound. Chronic/ non-healing/ contaminated ulcer is a frequently encountered problem in the present era commonly as a complication of trauma or pathological insult. Ayurveda mentions Vrana Shodhana (wound cleansing) and Vrana Ropna (wound healing) as treatment modalities under the Shasti Upkramas (60 specific treatment modalities for wounds). “No plant is devoid of medicinal values on this globe” as per Ayurvedic literature. Kapila shrub (Securinega leucopyrus linn), even though doesn’t find specific mention in Ayurvedic classics but as per above statement of “all plants are with medicinal properties”, is better used as folklore medicine for wound management.

Aims: Aim of the present study was to evaluate the efficacy of a folklore drug name Katupila over Dusta Vrana.

Methods and Material: This study includes efficacy analysis of Katupila drug as a Nirudhhalepa (smeared paste of Securinegaleucopyrus mixed with honey) for the management of DustaVrana over 30 numbers of patients who were fulfilling inclusion criteria. Daily application of Nirudhhalepa over Dustavrana was done with proper aseptic precautions until complete healing or 28 days whichever is earlier. During the study, weekly assessment according to assessment parameter was done and results were drawn accordingly.

Statistical analysis used: obtained data Analysis was done using SPSS version 23 (IBM SPSS Statistics Inc., Chicago, Illinois, USA) Windows software program. The data were checked for normality before statistical analysis using Shapiro–Wilk test. Friedman test was applied for repeated measures.

Results and conclusion: The data has shown encouraging results of wound healing to revalidate its use in wound management. All observations and results showed that Katupila Nirudhhalepa is promoting agent in the wound healing process.

Key messages: Present study validates data regarding the wound healing effect of a folklore drug named ‘Katupila’.

 

References

  • 1.   Sushruta Samhita, Sutrasthan , Vranastravavignaniya Adhyay, 22/7, Available from:https://niimh.nic.in/ebooks/esushruta
  • 2.   Sushruta Samhita, Sutrasthan, Vranastravavignaniya Adhyay, Chapter 22/7, Available from:https://niimh.nic.in/ebooks/
  • 3.   Sushruta Samhita, Sutrasthan, Vranastravavignaniya Adhyay, Chapter 22/5, Available from:https://niimh.nic.in/ebooks/
  • 4.   Soysa P, De Silva IS, Wijayabandara J, Evaluation of antioxidant and antiproliferative activity of Flueggea leucopyrus Willd (katupila), BMC Complement Altern Med. 2014;14:274.
  • 5.   Soysa P, De Silva IS, Wijayabandara J, Evaluation of antioxidant and antiproliferative activity of Flueggea leucopyrus Willd (katupila), BMC Complement Altern Med. 2014;14:274.
  • 6.   K Vijaya Kumari, K Nishteswar, Wound healing activity of honey: A pilot study, Ayu journal, 2012, 33 ,3/374-377.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

Provide information related to the Ethics Committee approval with approval number OR write, This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.

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Cite this article

Snehal R Sonani, Vivekanand Kullolli, Shailesh Jaiswal, et. al./Clinical Evaluation of Katupila Nirudhhalepa in Management
of Dusta Vrana/Indian J of Ancient & Yoga. 2022;15(4): 141–148.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
October 01, 2022 October 29, 2022 November 30, 2022
DOI: https://doi.org/10.21088/ijamy.0974.6986.15422.2

Keywords

DustaVrana; Katupila; Nirudhhalepa; Non-healing ulcer; Securinegaleucopyrus; Shasti Upkrama; Wound.

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Timeline

Received October 01, 2022
Accepted October 29, 2022
Published November 30, 2022

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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