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Bio-Chemical and Hematological Alterations Due to Toxicity of Dimicron Organophosphate Pesticide in Fish Clarias Batrachus

Mishra B. P.* , Mishra B. P.* , Bhupinder Kaur Anand** , Lingidi Jhansi Lakshmi*** , Sapna Jaiswal****

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Indian Journal of Medical and Health Sciences 2(1):p 15-22, Jan-Jun 2015. | DOI: DOI: https://dx.doi.org/10.21088/ijmhs.2347.9981.2115.3

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Abstract

Objective: To study the biochemical parameters of serum glutamate oxaloacetate transminase (SGOT), serum cholesterol and hematological parameters hemoglobin, total leucocyte count (TLC) in fish clarias batrachus, exposed under pesticide dimicron. Materials and Methods: This study was concluded in fish clarias batrachus exposed 24 to 96 hours to four different concentration of dimicron pesticide. Serum cholesterol, SGOT was estimated as bio-chemical biomarkers while hemoglobin and total leucocyte count as hematological biomarker. Result: There were significant increase in serum cholesterol, SGOT, TLC and altered hemoglobin observed in dimicron pesticide exposed to fish clarias batrachus. Conclusion: Hypercholesterolemia, elevated SGOT, leucocytosis and altered hemoglobin is result of toxicity of dimicron pesticide in fish clarias batrachus. The elevated cholesterol and SGOT are the biochemical biomarker for the disorder like myocardial infarction, heart attack, biliary obstruction, alcoholic cirrhosis etc in human beings. 
 
Keywords: OPP (Organophosphate Pesticide) SGOT (Serum Glutamate Oxaloacetate Transminase) Dimicron, TLC (Total Leucocyte Count). 

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DOI: DOI: https://dx.doi.org/10.21088/ijmhs.2347.9981.2115.3

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