Abstract

Background: Hypertension and dyslipidemias are major risk factors for Coronary artery disease. It is well known that diabetes mellitus associated with dyslipidemias. But hypertension associated with abnormal lipid profile Also can occur. Various studies Have shown that lipid levels are abnormally high in Hypertensive patients compared to control group. It appears that Dyslipidemias and hypertension may also have synergistic effect on atherosclerosis. Aim and Objective: (1) To study the lipid values in hypertensive individuals. (2) Comparison of lipid values between smokers and non smokers with hypertension. (3) Comparison of lipid values between obese and non obese patients with hypertension. (4) Age wise distribution of hyperlipidemia. Material and Methods: This prospective randomized clinical study entitled “A Study on Lipid Profile in Hypertensive Patients” A cros-sectional study was conducted after clearance from Board of Studies and Ethical committee in the Department of General Medicine at Rajshree medical and research institute and hospital during the period 2021-2022. The total sample size was determined to be 157 patients. Results: Among study population, majority belonged to 40-50 years age group (52.9%) followed by 51-60 years (31.2%) and above 60 years (15.9%). The risk factors reported were Obesity (52.2%), Smoking (66.9%) and Alcohol (44.6%). Among the hypertensive patients Raised Total Cholesterol, LDL and Triglycerides was reported as 61.8%, 49.0% and 65.6% respectively. Low HDL was reported among 58.6% subjects. There was a significantly positive correlation of age with Total Cholesterol, LDL, Triglycerides (61.8%, 49%, 65% respectively). Low HDL was reported among 58.6% subjects. There was a significantly negative correlation of age with HDL. Raised Total Cholesterol, LDL and Triglycerides was significantly more among smokers (73.1%, 59.6% and 75.0% respectively) compared to non-smokers (56.2%, 43.8% and 61.0%). Raised Total Cholesterol, LDL and Triglycerides was significantly more among obese people (96.3%, 92.7%, and 92.7% respectively) low HDL (100%) was significantly more among obese people. Conclusion: In the research area hypertension individuals had a significant frequency of abnormal lipid profiles and poorly managed blood pressure, according to the study findings. Significantly more overweight and obese individuals had hypertension than normal. There was significantly positive correlation of age, smoking, Obesity with total cholesterol, triglycerides, LDL, VLDL and negative correlation with HDL.

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