Abstract

Neurocystecercosis (NCC) is one of major endemic zoonotic disease in India. NCC is a common disease of the central nervous system, caused by Taeniasolium, a parasite spreading after consumption of undercooked pork. NCC majorly presents as epilepsy, an is diagnosed by radiological support like the computed tomography CT) and magnetic resonance imaging (MRI). The most common presentation of NCC is headache and seizure. The treatment is usually cysticidal drugs initiation like albendazole and praziquantel etc, but neurosurgical intervention is also advocated at regular intervals depending on the disease presentation and clinical profile of the patient. The presentation of NCC with acute meningitis is minimally reported in the literature and has very less occurrence in the field. In this case report, we discuss an interesting case of acute meningitis due to underlying neurocysticercosis, the challenges in diagnosis and treatment protocol, the final outcome in acute meningitis with NCC.

• 1.   Garcia H.H., Gonzalez A.E., Gilman R.H.: Diagnosis, treatment and control of Taenia solium cysticercosis. Curr Opin Infect Dis. 2003, 16: 411-419.
• 2.   CDC. Parasites – cysticercosis [Online].
• 3.   WHO. Taeniasis/Cysticercosis [Online].
• 4.   Roman, J. Sotelo, O.D. Brutto, A. Flisser, M. Dumas, N. Wadia, et al. A proposal to declare neurocysticercosis an international reportable disease
• 5.   Marcin Sierra M., Arroyo M., Cadena Torres, et al. Extra parenchymal neurocysticercosis: demographic, clinic radiological, and inflammatory features. Plos Negl Trop Dis. 2017, 11: 0005646.
• 6.   Kelesidis T., Tsiodras S: Extraparenchymal neurocysticercosis in the United States. Am J Med Sci. 2012, 1: 79 82. 10.1097/ MAJ.0b013e31823e6565.
• 7.   White A.C. Jr, Coyle C.M., Rajshekhar V., et al. Diagnosis and treatment of neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious. Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis. 2018, 66: 1159-1163.
• 8.   Wallin M.T., Kurtzke J.F. Neurocysticercosis in the United States: review of an important emerging infection . Neurology. 2004, 9:1559- 1564. 10.1212/01.wnl.0000142979.98182.ff.
• 9.   Earnest M.P., Reller L.B., Filley C.M., Grek A.J. Neurocysticercosis in the United States: 3S cases and a review. Rev Infect Dis. 1987, 5:961- 979. 10.1093/clinids/9.5.961
• 10.   P. Singhi – Neurocysticercosis Ther Adv Neurol Disord, 4 (2) (2011), pp. 67-81
• 11.   UpToDate. Epidemiology, transmission and prevention of cysticercosis [Online].
• 12.   Garcia H.H., Nash T.E., Del Brutto O.H. Clinical symptoms, diagnosis, and treatment of neurocysticercosis. Lancet Neurol. 2014, 13:1202-1215. 10.1016/S1474-4422(14)70094-8.
• 13.   Landscape analysis: management of neurocysticercosis with an emphasis on lowand middle-income countries. (2015).
• 14.   Del Brutto O.H., Nash T.E., White A.C. Jr, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017 Jan, 15: 202-210.
• 15.   Gabriel S., Blocher J., Dorny P., et al. Added value of antigen ELISA in the diagnosis of neurocysticercosis in resource poor settings. PLoS Negl Trop Dis. 2012, 6: 1851. 10.1371/ journal.pntd.0001851

Data Sharing Statement

Funding