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A Prospective Observational Study on Clinical Profile, Laboratory Parameter and Outcomes of Rodenticide Poisoning

Manjunath null, Shyamala G.

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Indian Journal of Medical and Health Sciences 11(2):p 77-86, Oct - Dec. 2024. | DOI: https://doi.org/10.21088/ijmhs.2347.9981.11224.4

How Cite This Article:

Shyamala G., Manjunath, A Prospective Observational Study on Clinical Profile, Laboratory Parameter and Outcomes of Rodenticide Poisoning. Jr. Med. & Health Sci. 2024;11(2):77–86.

Timeline

Received : October 21, 2024         Accepted : November 11, 2024          Published : December 30, 2024

Abstract

Introduction: In India, rodenticide poisoning poses a serious threat to public health due to its high rate of morbidity and mortality. The purpose of this study was to assess rodenticide poisoning’s clinical characteristics, laboratory results, and outcomes at an Indian tertiary care facility. Material and Methods: 50 patients with rodenticide poisoning who were hospitalized to a tertiary care facility in India for a period of one and a half years participated in a prospective observational research. Results were assessed in connection to the type of rodenticide consumed, and clinical symptoms, indicators, and laboratory parameter evaluations were conducted. Results: In our investigation, the prevalence of rodenticide poisoning throughout the study period was 6.7%. The bulk of the people (58.00%) are under the age of twenty decades. Vomiting (38%) and abdominal discomfort (22%) were the most common symptoms. Clinically, icterus was the most prevalent sign (38%) of all. Symptoms (p=0.043), signs (p=0.040), rodenticide kind (p=0.003), amount of rodenticide consumed (0.038), and metabolic acidosis presence (p=0.001) were all significantly correlated with survival status. Patients who passed away had considerably worse liver function tests, coagulation profiles, and renal functions than those who survived (p<0.05). There was a 12% overall mortality rate. Conclusion: Young adults are the age group most affected by rodenticide poisoning, which is linked to considerable morbidity and mortality. Improving patient outcomes requires early detection, timely treatment, and careful observation.In environments with limited resources, the findings of this study can direct the creation of evidence-based management plans and preventative actions for rodenticide poisoning.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Shyamala G., Manjunath, A Prospective Observational Study on Clinical Profile, Laboratory Parameter and Outcomes of Rodenticide Poisoning. Jr. Med. & Health Sci. 2024;11(2):77–86.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator


Received Accepted Published
October 21, 2024 November 11, 2024 December 30, 2024

DOI: https://doi.org/10.21088/ijmhs.2347.9981.11224.4

Keywords

Rodenticide poisoningClinical profileLaboratory parametersOutcomestertiary care centerIndia

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Received October 21, 2024
Accepted November 11, 2024
Published December 30, 2024

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator


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