Manjunath null 3rd Year Post Graduate Resident, Department of General Medicine, Ballari Medical College and Research Center, Karnataka 583104, India
Shyamala G. Professor and Unit Chief, Department of General Medicine, Ballari Medical College and Research Center, Karnataka 583104, India
Address for correspondence: Manjunath null, 3rd Year Post Graduate Resident, Department of General Medicine, Ballari Medical College and Research Center, Karnataka 583104, India E-mail: drmanjunathtelagade@gmail.com
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Shyamala G., Manjunath, A Prospective Observational Study on Clinical Profile, Laboratory Parameter and Outcomes of Rodenticide Poisoning. Jr. Med. & Health Sci. 2024;11(2):77–86.
Timeline
Received : October 21, 2024
Accepted : November 11, 2024
Published : December 30, 2024
Abstract
Introduction: In India, rodenticide poisoning poses a serious threat to public health due to its high rate of morbidity and mortality. The purpose of this study was to assess rodenticide poisoning’s clinical characteristics, laboratory results, and outcomes at an Indian tertiary care facility. Material and Methods: 50 patients with rodenticide poisoning who were hospitalized to a tertiary care facility in India for a period of one and a half years participated in a prospective observational research. Results were assessed in connection to the type of rodenticide consumed, and clinical symptoms, indicators, and laboratory parameter evaluations were conducted. Results: In our investigation, the prevalence of rodenticide poisoning throughout the study period was 6.7%. The bulk of the people (58.00%) are under the age of twenty decades. Vomiting (38%) and abdominal discomfort (22%) were the most common symptoms. Clinically, icterus was the most prevalent sign (38%) of all. Symptoms (p=0.043), signs (p=0.040), rodenticide kind (p=0.003), amount of rodenticide consumed (0.038), and metabolic acidosis presence (p=0.001) were all significantly correlated with survival status. Patients who passed away had considerably worse liver function tests, coagulation profiles, and renal functions than those who survived (p<0.05). There was a 12% overall mortality rate. Conclusion: Young adults are the age group most affected by rodenticide poisoning, which is linked to considerable morbidity and mortality. Improving patient outcomes requires early detection, timely treatment, and careful observation.In environments with limited resources, the findings of this study can direct the creation of evidence-based management plans and preventative actions for rodenticide poisoning.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Shyamala G., Manjunath, A Prospective Observational Study on Clinical Profile, Laboratory Parameter and Outcomes of Rodenticide Poisoning. Jr. Med. & Health Sci. 2024;11(2):77–86.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator