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A Comparative Study of Dexmedetomidine and Clonidine as Adjuvant to Propofol for Insertion of Laryngeal Mask Airway

Vishalakshi Patil, Assistant Professor, Dept of Anesthesiology &Critical Care, Navodaya Medical College Hospital and Research Centre, Raichur – 584103, Karnataka, India , Allauddin Farooqy* , Vishalakshi Patil* , Shashikala Ramakrishna** , Mohammed Mohsine Ali** , Mohammed Shakeeb Yusufl**

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Indian Journal of Anesthesia and Analgesia 4(2):p 491-495, April - June 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.22

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Abstract

Objective:To evaluate theease of insertion ofLaryngeal Mask Airway (LMA) and hemodynamic response during insertion of LMA with two adjuvants, dexmedetomidine & clonidine along with induction agent propofol. Methods: Hundred patients scheduled for elective surgical procedures were recruited in this study. The hemodynamic effects and ease of insertion of LMA with adjuvants, dexmedetomidine & clonidine with propofol was compared. The hemodynamic responses were assessed byheart rate, non-invasive blood pressure, respiratory rate and oxygen saturation. The overall conditionof patient was assessed according to modified scheme of Lund and Stovener. The condition of insertion was assessed as jaw relaxation and response to LMA insertion in the form of coughing, gagging, laryngospasm and involuntary limb movements. Results: The incidence of coughing, gagging, laryngospasm and involuntary limb movements were comparable in both the group, whereas, jaw relaxation, overall insertion condition and hemodynamic responses were better {p value for heart rate:<0.001} in dexmedetomidine group.Conclusion: Dexmedetomidine as an adjuvant to propofol  provides better LMA insertion conditions, fewer side effects & prevent hemodynamic response to LMA insertion compared to clonidine.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.22

Keywords

LMA Insertion; Propofol; Dexmedetomidine; Clonidine.

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