Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

A Comparative Study between Intrathecal Clonidine and Buprenorphine with Intrathecal Bupivacaine for Lower Abdominal Surgeries

Yoganarasimha N* , Yoganarasimha N* , Amitha S.** , Shridhar K.***

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 4(1):p 107-112, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4117.17

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

 Purpose: Subarachnoid (spinal) block is a safe and effective alternative to general anesthesia when the surgical site is located on the lower extremities, perineum (eg, surgery on the genitalia or anus), or lower body wall (eg, inguinal herniorrhaphy).  In no other way, can an anaesthesiologist obtain so much of an effect for the introduction of a small quantity of the drug. Likewise a properly chosen adjuvant to local anaesthetic agent produces the best way to achieve a good quality regional block. Aim of Study: To compare the effect of intrathecal Clonidine 75 micrograms (µg) and Buprenorphine 150 µg with 2.5ml (12.5mg) of intrathecal 0.5% hyperbaric Bupivacaine. With regards to: 1) Sensory characteristics, 2) Motor characteristics, 3) Hemodynamic stability and 4) Side effects. Methodology: A prospective randomized experimental study were performed on 50 patients posted for lower abdominal surgery belonging to ASA I and aged between18­60 years after obtaining an informed consent and ethical clearance. Result: Addition of 150 µg Buprenorphine significantly enhances the onset of sensory block (90±15 secs) and motor block (150±15 secs) than compared to Clonidine onset of sensory block(150±20 secs) and motor block(210±20 secs) (p<0.05). Hemodynamic was well maintained with buprenorphine group. And addition of Buprenorphine 150µg to intrathecal Bupivacaine(0.5%) produces prolonged analgesia (526±96) than compared to the Clonidine group of 362±36mins (p<0.05) with no serious adverse effect noted perioperatively in either groups. Conclusion: The addition of Buprenorphine to intrathecal Bupivacaine (0.5%) prolongs the duration of post operative analgesia than compare to clonidine. Buprenorphine has faster onset of sensory and motor blockade than compare to clonidine.

Keywords: Clonidine; Buprenorphine; Hyperbaric; Lower Abdominal Surgery Analgesia; Bromage Scale [1].

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4117.17

Keywords


Article Level Metrics

Last Updated

Monday 13 July 2026, 12:28:54 (IST)

5653

Accesses

4
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share