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A Comparative Study between Dexmedetomidine 1 µg/kg and and 25mg/ kg of 50% Magnesium Sulphate as Adjuvants with 0.5% Lidocaine for Intravenous Regional Anaesthesia

Jagadish Vaddineni, Assistant Professor, Department of Anaesthesiology, Narayana Medical College, Nellore, Andhra Pradesh 524003, India. , Kandukuru Krishna Chaithanya1 , Jagadish Vaddineni2 , Abdul Ansari3 , P. Narasimha Reddy4 , Jayanth5 , Priyanka6

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Indian Journal of Anesthesia and Analgesia 5(2):p 326-330, February 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5218.28

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Abstract

Introduction: Intravenous regional anaesthesia (IVRA) also called as Bier’s block is a commonly used anaesthetic technique for surgical procedures on the upper extremities. Many adjuvants have been used to improve the quality of intravenous regional anaesthesia (IVRA). Aims and objectives: The aim of this study was to compare the use of dexmedetomidine and magnesium sulphate as adjuvants lidocaine for IVRA as regards to onset and duration of sensory and motor blocks, hemodynamic variables. Materials and Methods: This prospective, randomized, double-blinded trial was conducted in 60 ASA I and II patients scheduled for upper hand and forearm surgeries who were randomly divided into two groups, comprising 30 patients each. Group D received dexmedetomidine 1mic/kg and 0.5% lidocaine to a total volume of 40 ml, whereas group M received 25mg/kg of 50% magnesium sulphate and 0.5% lidocaine to a total volume of 40 ml. Onset and duration of sensory and motor block, hemodynamic variables were recorded and compared between the two groups. Results: There was statistically significant difference between both the groups as group D achieved rapid onset and prolonged duration of sensory and motor block compared to group M (p<0.0001). Group D showed significant difference in heart rate and mean arterial pressure compared to group M after the tourniquet deflation. (p<0.0001). Conclusion: Our study shows that Dexmedetomidine provides rapid onset and prolonged duration of sensory and motor block in Intravenous regional anaesthesia compared to magnesium sulphate.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5218.28

Keywords

Intravenous Regional Anaesthesia; Dexmedetomidine; Lidocaine; Magnesium Sulphate. 

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