Ophthalmology and Allied Sciences

 Not Provided.

Progressive cone dystrophies represent a heterogeneous group of diseases with onset in later teens and adult age diagnosed by an abnormal photopic electroretinographic response and a normal or near-normal rod isolated response. We report the case of a young male with typical characteristics of cone dystrophy and a brief description about the inheritance pattern and pathology of the disease.Progressive cone dystrophies represent a heterogeneous group of diseases with onset in later teens and adult age diagnosed by an abnormal photopic electroretinographic response and a normal or near-normal rod isolated response. We report the case of a young male with typical characteristics of cone dystrophy and a brief description about the inheritance pattern and pathology of the disease. 

Keywords: Orbital Cellulites; Osteogenic Sarcoma; Parietal Bone; Orbit; Infra-Temporal Fosse; Extraconal Lesion 

Keywords: Tuberculosis; Choroiditis; Periviascultitis; Optic atrophy; Papilloedema; Ethambutol Toxicity. 

Keywords: Intraocular Pressure; Humphrey’s Visual Field Analysis; Field Workers; Vision Centers; Nd: YAG lasers. 

 Objective: To study the anatomic and visual outcomes of descemetopexy in Descemet’s membrane detachment (DMD) after cataract surgery with the help of Anterior Segment –OCT (AS-OCT) and endo-illuminator. Design: A prospective study. Participants: Nineteen eyes of 19 patients. Methods: This study was carried out at Regional Institute of Ophthalmology (M.D. Eye Hospital, Dr. Katju Road, Nakhas Kona, Allahabad, India) after taking permission from ethical committee of M.L.N. Medical College, Allahabad from April 2013 to March 2014. We used Anterior segment OCT (AS-OCT) and endoilluminator in the management of Descemet’s membrane detachment. Descemetopexy was performed with air or 14% isoexpansile perfluoropropane (C3F8) or 20% SF6 gas. Main Outcome Measures: Anatomical (reattachment rates) and functional results (best-corrected visual acuity) were studied. Secondary outcome measures were assessment of surgical complications and association of various factors with final visual outcome. Results: With the help of endo-illuminator and OCT, we treated total 19 patients of Descemet’s membrane detachment following cataract surgery with intra-cameral injection of air (3 patients), perfluoropropane (7 patients) and sulphur hexafluoride (9 patients), figure 2. Out of the 19 patients 13 (68%) patients had final visual acuity between 6/6-6/12 and 6 (32%) patients had final visual acuity between 6/12-6/24, figure 3. Reattachment occurred within 48 hours in 15 patients and after 48 hours in 4 patients. Residual DMD was found in one case in which we re-injected SF6. Conclusion: Anterior Segment Optical Coherence Tomography(OCT) guided, endo-illuminator assisted intra-cameral injection of sulphur hexafluoride (SF6) gas is the best way of management of Descemet’s membrane detachment as compared to intra-cameral injection of air and perfluoropropane (C3F8) gas. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Aim: To study the correlation between altered serum lipid profile and spectral domain optical coherence tomography (SD-OCT) based macular thickness parameters in diabetic retinopathy. Method: Study subjects included 60 cases of type 2diabetes mellitus (DM): no diabetic retinopathy (No DR, n=20); non proliferative DR (NPDR, n=20); proliferative DR (PDR, n=20) and 20 healthy controls. Best corrected visual acuity (BCVA) was measured on logMAR scale. Cube average thickness (CAT) and central subfield thickness (CST) was assessed using SD-OCT. Serum lipid profile was analyzed using standard protocol. Data was analyzed statistically. Result: Decrease in BCVA positively correlated with increased CAT (r=0.25, p=0.028), increased CST (r=0.28, p=0.04), increased serum cholesterol (r=292, p=0.01) and decreased high density lipoprotein (r=-0.714, p=0.01). Statistically significant positive correlation was found between increase in CAT with increase in serum cholesterol (r=0.403, p=0.00) and also with increase in low density lipoprotein (r=0.343, p=0.02.). Conclusion: Deranged lipid profile correlates with the progression of diabetic retinopathy. Further, this study demonstrates the correlation of deranged lipid profile and decreased visual acuity with increased CAT.

Keywords: Diabetic Retinopathy; Lipid Profile; Spectral Domain Optical Coherence Tomography; Cube Average Thickness; Central Subfield Thickness. 

 Not Provided.