Journal of Dermatology

Introduction: Micrrodermabrasion (MDA) is an office procedure for various skin conditions with minimal invasion. This study's aim was to determine efficacy and side effects of MDA in different dermatoses. Method: This was an interventional prospective study including 45 subjects. Inclusion criteria pertained to cases having superficial acne scars, superficial wrinkling, mild to moderate acne with post inflammatory hyper pigmentation, acanthosis nigircans and melasma who were ready for regular follow up biweekly among other things. Pre-procedural care included avoidance of certain procedures and priming of skin was done. Detailed history, examination and investigations were done for all patients. Bimanual technique for MDA was used after giving proper position to the patient. Series of multiple linear sweeping movements were done using handpiece. 2nd pass was carried out perpendicular to the first pass. Post procedural instructions were vigilantly given. Results: Out of the 45 cases enrolled, 20 were male and 25 were female of ages 11 to more than 40. No patients showed 100% improvement, minimal to moderate improvement was seen in maximum patients, while some patients of melasma, post acne scarring and mild to moderate acne showed no improvement at all. Side effects like mild erythema persisting for one to two hours was seen in fifteen patients and irritation in eyes was seen in six patients which usually disappeared after washing. Conclusion: MDA is a simple and safe office procedure suited for superficial resurfacing problems that does not interfere with normal activities of the patient and has minimal side effect.

Skin grafts are commonly used in plastic and reconstructive surgery. Chronic wounds are linked to a patient's delayed healing and increased morbidity. Flaps, skin grafting, temporary alternatives for dressings, and other types of wound coverage are available. In this case study, we tested the efficiency of a novel approach of Suction Assisted Epidermal Blister Grafting for a raw area cover.

Many medications are now administered orally; however they are not as effective as they should be. Beyond the local application site, transdermal delivery technology is being explored to treat a wide range of diseases. Because of reduced first pass metabolism, avoidance of an adverse gastrointestinal environment, and the potential to provide extended and regulated drug delivery, transdermal drug administration offers substantial benefits over oral treatment. Transdermal drug delivery systems (TDDS) are topically applied patches that release medications for systemic effects at a predetermined and regulated rate. It works by putting a medication inside a patch and wearing it for a long time on the skin. As a result, a steady concentration of medication remains in the bloodstream for an extended period of time. TDDS products include Scopolamine, Nicotine, Testosterone, Fentanyl, and Clonidine. Numerous active compounds with variable molecular size and structure cannot be maintained in transdermal form, despite their many benefits.