Indian Journal of Maternal-Fetal & Neonatal Medicine

Obstetrics is a speciality dealing with two lives, closely linked, whose interests may not coincide. Due to rapid expansion of medical technology, obstetricians have to face complex ethical questions. Surrogacy has given a new dimension to the concept of a traditional family. Surrogacy offers hope to couples to produce their own genetic family. Fetal therapy is an exciting new field of expertise with expanding indications. The medical community is benefitted by these innovative therapies. The greatest care should be taken in explaining findings of congenital malformations to the parents, sympathetic approach, understanding and reassurance are important. 

A descriptive research design was used to assess the level of knowledge and attitude of Mothers Regarding Growth of Under Five Children in a selected hospital, Kottayam. The study was conducted in little Lourdes college of nursing kidangoor. The study samples consist of 30 mothers of under five children who came to pediatric and gynecology outpatient departments and wards. Samples are selected by using convenient sampling technique. Structured knowledge questionnaire and 3 point attitude scale used to collect data. The result shows that among 30 samples 6 (20%) of mothers had poor knowledge and 24 (80%) of mothers had average level of knowledge. Among 30 samples 14 (46.6%) of mothers had moderately positive attitude, 16 (53.3%)of mothers had positive attitude towards the growth of under five children. The study findings revealed that there is a significant correlation between knowledge and attitude of mothers regarding the growth of under five children (r=0.63)

Objective: The objective of the study was to study the effect of 75 mg and 150 mg aspirin in prevention of pre-eclampsia in women with previous history of pre-eclampsia.

Method: This prospective interventional study was carried out in the Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS, Rohtak from 2019-2020. Women with previous history of pre-eclampsia who presented at period of gestation less than 16 weeks were included in the study. The patients were divided in two groups, Group-I: 50 patients who received aspirin, 75 mg daily and Group-II: 50 patients who received aspirin, 150 mg daily.

Results: Group I (75 mg of aspirin) and Group II (150 mg of Aspirin) were comparable with respect to age, education and socio-economic status. The mean gestational age of delivery was also comparable. Overall Incidence of pre-eclampsia in present study was 14%. Pre-eclampsia occurred in 8 (16%) women in group-I and 6 (12%) women in group-II. The difference was found to be statistically insignificant. Perinatal complications like low birth weight, preterm delivery, NICU transfer, respiratory distress syndrome and fetal growth restriction were not significantly different in both the groups.

Conclusion: There is no correlation between 75 mg versus 150 mg dose of aspirin and the incidence of pre-eclampsia in women with previous history of pre-eclampsia. Also, 150 mg aspirin had no statistically significant effect on the incidence of secondary outcome (Abruptio placenta, any maternal morbidity, fetal outcome intrauterine growth restriction, intrauterine death, NICU admission, NICU stay and perinatal death) in comparison to 75 mg aspirin.