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Where to Bind, Hemoglobin or Methemoglobin: Confused Oxygen

A. Josephine Leshiini, Priya Govil, Kishalay Datta

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Indian Journal of Emergency Medicine 9(2):p 93-95, April-June 2023. | DOI: 10.21088/ijem.2395.311X.9223.7

How Cite This Article:

Leshiini AJ, Govil P, Datta K. Where to Bind, Hemoglobin or Methemoglobin: Confused Oxygen. Indian J Emerg Med. 2023;9(2):93–5.

Timeline

Received : February 13, 2023         Accepted : March 07, 2023          Published : April 09, 2023

Abstract

Methemoglobinemia is a life-threatening condition in which there is a decrease in the oxygen carrying capacity of the blood (hemoglobin). The relative hypoxemia leads to fall in patient blood saturation without any breathing difficulty. We discuss a case of methemoglobinemia in a young adult with leprosy, the presentation and management of the condition in the Emergency room.


References

  • 1.   Curry S. Methemoglobinemia. Ann Emerg Med. 1982 Apr;11(4):214-21.
  • 2.   Haymond S, Cariappa R, Eby CS, Scott MG. Laboratory assessment of oxygenation in methemoglobinemia. Clin Chem. 2005 Feb;51(2):434-44.
  • 3.   Percy MJ, Lappin TR. Recessive congenital methemoglobinemia: cytochrome b(5) reductase deficiency. Br J Haematol. 2008 May;141(3):298-308.
  • 4.   Bradberry SM. Occupational methemoglobinemia. Mechanisms of production, features, diagnosis and management including the use of methylene blue. Toxicol Rev. 2003;22(1):13-27.
  • 5.   Guay J. Methemoglobinemia related to local anesthetics: a summary of 242 episodes. Anesth Analg. 2009 Mar;108(3):837-45.
  • 6.   Hall RP, Mickle CP. Dapsone. In: Wolverton SE, editor. Comprehensive Dermatologic Drug Therapy. 2nd ed. Philadelphia: Saunders; 2007. p. 239–53.
  • 7.   Wright RO, Lewander WJ, Woolf AD. Methemoglobinemia: etiology, pharmacology, and clinical management. Ann Emerg Med. 1999 Nov;34(5):646-56.
  • 8.   Nappe TM, Pacelli AM, Katz K. An Atypical Case of Methemoglobinemia due to Self-Administered Benzocaine. Case Rep Emerg Med. 2015;2015:670979.
  • 9.   Barker SJ, Badal JJ. The measurement of dyshemoglobins and total hemoglobin by pulse oximetry. Curr Opin Anaesthesiol. 2008;21(6):805–10.
  • 10.   Blanc PD. Methemoglobinemia. In: Olson KR, editor. Poisoning and Drug Overdose. 3rd ed. Norwalk: Appleton and Lange; 1999. p. 217–9.
  • 11.   Atyabi N, Yasini SP, Jalali SM, Shaygan H. Antioxidant effect of different vitamins on methemoglobin production: An in vitro study. Vet Res Forum. 2012;3(2):97–101.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication."

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

Information not provided.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Leshiini AJ, Govil P, Datta K. Where to Bind, Hemoglobin or Methemoglobin: Confused Oxygen. Indian J Emerg Med. 2023;9(2):93–5.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
February 13, 2023 March 07, 2023 April 09, 2023

DOI: 10.21088/ijem.2395.311X.9223.7

Keywords

Methemoglobinemia; Methylene blue; Tablet Dapsone.MethemoglobinemiaMethylene blueTablet Dapsone

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Timeline


Received February 13, 2023
Accepted March 07, 2023
Published April 09, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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