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The Paradox of Clot and Bleed: A Rare Presentation of Extensive Cerebral Venous Thrombosis with Subarachnoid Hemorrhage in a Young Woman

Niveditha Balakrishnan, Akhil A.B, Omana Rajan

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Indian Journal of Emergency Medicine 11(4):p 241-251, Oct - Dec. 2025. | DOI: https://doi.org/10.21088/ijem.2395.311X.11425.6

How Cite This Article:

Akhil AB, Balakrishnan N, Rajan O. The Paradox of Clot and Bleed: A Rare Presentation of Extensive Cerebral Venous Thrombosis with Subarachnoid Hemorrhage in a Young Woman. Ind J Emerg Med. 2025;11(4):241-51.

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Received : July 14, 2025         Accepted : October 22, 2025          Published : December 30, 2025

Abstract

Background: Cerebral venous thrombosis (CVT) is an uncommon but important cause of stroke, more frequently seen in young females. Several risk factors have been identified, including pregnancy, the puerperium, anemia, polycystic ovarian syndrome (PCOS), and the use of oral contraceptive pills (OCPs). Case Presentation: We report the case of a 23-year-old woman who presented to the emergency department with a sudden-onset, severe thunderclap headache. She had been on combined oral contraceptive pills (ethinyl estradiol 0.03 mg + desogestrel 0.15 mg, Miliana) for the past three months for menstrual cycle regulation. Neuroimaging revealed cerebral venous thrombosis complicated by subarachnoid hemorrhage (SAH) a rare and diagnostically challenging presentation.Management and Outcome: The patient was managed with anticoagulation under close neurological monitoring, with careful discontinuation of OCPs. Despite the initial severity, she made a complete neurological recovery.Conclusion: This case highlights the need for heightened clinical suspicion of CVT in young women presenting with severe headache, especially those on hormonal contraceptives. Early diagnosis and appropriate anticoagulation, even in the presence of SAH, can result in favourable outcomes. A multidisciplinary approach is essential in managing the complexities of such cases


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Akhil AB, Balakrishnan N, Rajan O. The Paradox of Clot and Bleed: A Rare Presentation of Extensive Cerebral Venous Thrombosis with Subarachnoid Hemorrhage in a Young Woman. Ind J Emerg Med. 2025;11(4):241-51.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
July 14, 2025 October 22, 2025 December 30, 2025

DOI: https://doi.org/10.21088/ijem.2395.311X.11425.6

Keywords

Cerebral venous thrombosisSubarachnoid hemorrhageOral contraceptivesAnticoagulationStrokeYoung femaleVenous sinus thrombosisHemorrhagic infarction

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Received July 14, 2025
Accepted October 22, 2025
Published December 30, 2025

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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