Niveditha Balakrishnan Head and Consultant, Department of Emergency Medicine, Manipal Hospital, Jayanagar, Bengaluru, Karnataka, India
Akhil A.B 3rd Year Resident, Department of Emergency Medicine, Manipal Hospital, Jayanagar, Bengaluru, Karnataka, India
Omana Rajan 3 Registrar, Department of Emergency Medicine, Manipal Hospital, Jayanagar, Bengaluru, Karnataka, India
Address for correspondence: Niveditha Balakrishnan, Head and Consultant, Department of Emergency Medicine, Manipal Hospital, Jayanagar, Bengaluru, Karnataka, India E-mail: nivebala3102@gmail.com
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Akhil AB, Balakrishnan N, Rajan O. The Paradox of Clot and Bleed: A Rare Presentation of Extensive Cerebral Venous Thrombosis with Subarachnoid Hemorrhage in a Young Woman. Ind J Emerg Med. 2025;11(4):241-51.
Timeline
Received : July 14, 2025
Accepted : October 22, 2025
Published : December 30, 2025
Abstract
Background: Cerebral venous thrombosis (CVT) is an uncommon but important cause of stroke, more frequently seen in young females. Several risk factors have been identified, including pregnancy, the puerperium, anemia, polycystic ovarian syndrome (PCOS), and the use of oral contraceptive pills (OCPs). Case Presentation: We report the case of a 23-year-old woman who presented to the emergency department with a sudden-onset, severe thunderclap headache. She had been on combined oral contraceptive pills (ethinyl estradiol 0.03 mg + desogestrel 0.15 mg, Miliana) for the past three months for menstrual cycle regulation. Neuroimaging revealed cerebral venous thrombosis complicated by subarachnoid hemorrhage (SAH) a rare and diagnostically challenging presentation.Management and Outcome: The patient was managed with anticoagulation under close neurological monitoring, with careful discontinuation of OCPs. Despite the initial severity, she made a complete neurological recovery.Conclusion: This case highlights the need for heightened clinical suspicion of CVT in young women presenting with severe headache, especially those on hormonal contraceptives. Early diagnosis and appropriate anticoagulation, even in the presence of SAH, can result in favourable outcomes. A multidisciplinary approach is essential in managing the complexities of such cases
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All authors contributed significantly to the work and approve its publication.
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This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Akhil AB, Balakrishnan N, Rajan O. The Paradox of Clot and Bleed: A Rare Presentation of Extensive Cerebral Venous Thrombosis with Subarachnoid Hemorrhage in a Young Woman. Ind J Emerg Med. 2025;11(4):241-51.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.