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The Effect of Soy Flour Consumption on Gonadotropins in Postmenopausal Women

Deviga Thirunavukkarasu, Tutor, All India Institute of Medical Sciences, (AIIMS), Basni Industrial Area, Phase2, Jodhpur, Rajesthan 342005, India. , Deviga Thirunavukkarasu* , Menda Balachandrarao Naidu**

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International Journal of Practical Nursing 5(3):p 139-143, Sep-Dec 2017. | DOI: http://dx.doi.org/10.21088/ijpn.2347.7083.5317.1

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Abstract

Soy is being considered as possible alternatives to hormone replacement therapy in postmenopausal period. This study was undertaken to evaluate the effect of two different quantity of soy flour on gonadotropins in postmenopausal women. The study was done in 75 postmenopausal women. These women were randomly divided into 3 groups (n=25). The study group I was given soy flour 25gm/day and the study group II was given soy flour 45g/day and the control group was given wheat flour 52 gm/day. Fasting blood samples were analyzed for serum Luteinizing Hormone (LH) and FollicleStimulating Hormone (FSH) at the beginning of therapy, 4 and 12 weeks after initiation of therapy. The hormone changes were analyzed statistically by using oneway repeated measure ANOVA and oneway ANOVA. The result showed that in control group the FSH and LH hormones level significant increased (p<0.001) over time. Whereas, in soy groups, serum LH and FSH levels were significantly decreased (p<0.001) over time. It indicated that daily intakes of soy flour either 25g or 45g may decrease the LH and FSH hormones. More so, those in 45g soy flour intake. In addition, the result observed that no correlation between the luteinizing hormone and follicular stimulating hormone in control group as well in soy groups.

Keywords: Luteinizing Hormone (LH); FollicleStimulating Hormone (FSH); Gonadotropins. 

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DOI: http://dx.doi.org/10.21088/ijpn.2347.7083.5317.1

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