Atit A Gawalkar Assistant Professor, Department of Cardiology, All India Institute of Medical Sciences, New Delhi 110029, India
Mohan Prasad Akkineni Senior Resident, Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
Krishna Prasad Akkineni Associate Consultant, Department of Cardiology, Apollo Hospital, Jubilee Hills, Hyderabad, India
Souvik Sardar Associate Consultant, Department of Cardiology, Manorama Hospitex, Nadia, West Bengal, India
Goutam Kintada Consultant, Department of Cardiology, Devender Reddy Superspeciality Hospital, Nirmal, Telangana, India
Address for correspondence: Atit A Gawalkar, Assistant Professor, Department of Cardiology, All India Institute of Medical Sciences, New Delhi 110029, India E-mail: atitgawalkar@gmail.com
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Mohan Prasad Akkineni, Krishna Prasad Akkineni, Souvik Sardar et. al, Simultaneous tombstone ST elevations in Anterior and Inferior Leads. Indian J Cardiovasc Med Surg. 2025;11(2): 75–78.
Timeline
Received : July 21, 2025
Accepted : August 12, 2025
Published : August 30, 2025
Abstract
ECG changes of ST elevation and reciprocal ST depressions are necessary for diagnosis of ST elevation myocardial infarction which requires urgent revascularization. The reciprocal changes are crucial and help to differentiate from other conditions like pericarditis. However, sometimes in myocardial infarction ST elevations can occur in both anterior and inferior leads which are electrically opposite leading to a confounding situation.
References
1. Sadanandan S, Hochman JS, Kolodziej A, et al. Clinical and angiographic characteristics of patients with combined anterior and inferior ST-segment elevation on the initial electrocardiogram during acute myocardial infarction. Am Heart J. 2003 Oct;146(4):653-61.
2. Zheng J, Lin J, Shen N, et al. Proximal complete occlusion of right coronary artery presenting with precordial ST-segment elevation: A case report. Medicine (Baltimore). 2016 Oct;95(41):e5113.
3. Guo XH, Yap YG, Chen LJ, et al. Correlation of coronary angiography with “tombstoning” electrocardiographic pattern in patients after acute myocardial infarction. Clin Cardiol. 2000 May;23(5):347-52.
4. Pollak PM, Parikh SV, Kizilgul M, et al. Multiple culprit arteries in patients with ST segment elevation myocardial infarction referred for primary percutaneous coronary intervention. Am J Cardiol. 2009 Sep 1;104(5):619-23.
5. Goel S, Narang R, Gawalkar AA. Challenges in localisation of culprit artery in STEMI. J Electrocardiol. 2025 Feb 21;90:153901.
6. Rioufol G, Finet G, Ginon I, et al. Multiple atherosclerotic plaque rupture in acute coronary syndrome: a three-vessel intravascular ultrasound study. Circulation. 2002 Aug 13;106(7):804-8.
7. Møller JE, Engstrøm T, Jensen LO, et al; DanGer Shock Investigators. Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock. N Engl J Med. 2024 Apr 18;390(15): 1382-1393.
8. Yip HK, Chen MC, Wu CJ et al. Acute myocardial infarction with simultaneous ST-segment elevation in the precordial and inferior leads: evaluation of anatomic lesions and clinical implications. Chest. 2003 Apr;123(4):1170-80.
9. Jim MH, Chan AO, Tang MO et al. Angiographic and clinical implications of combined STsegment elevation in anterior and inferior leads in acute myocardial infarction. Clin Cardiol. 2009 Jan;32(1):21-7.
10. Alzand BS, Gorgels AP. Combined anterior and inferior ST-segment elevation Electrocardiographic differentiation between right coronary artery occlusion with predominant right ventricular infarction and distal left anterior descending branch occlusion. J Electrocardiol. 2011 May-Jun;44(3):383-8.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Mohan Prasad Akkineni, Krishna Prasad Akkineni, Souvik Sardar et. al, Simultaneous tombstone ST elevations in Anterior and Inferior Leads. Indian J Cardiovasc Med Surg. 2025;11(2): 75–78.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.