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Silent Corticotroph Adenoma Presenting with Diabetes Insipidus: A Case Report

Sridhara Narayana Vuddagiri , Sridhara Narayana Vuddagiri , Alugolu Rajesh , Dinesh Shukla , Megha Shantveer Uppin , Challa Sundaram

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International Journal of Neurology and Neurosurgery 5(2):p 71-76, July - December 2013. | DOI:

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Abstract

Background: Silent corticotroph adenoma (SCA) is a rare sub-type of non-functioning pituitary tumour and like other macroadenomas, they usually present with symptoms related to compression of the adjacent structures, but still Diabetes insipidus is rarely seen in SCA’s. Case report: We report a 42 year old female presenting with left visual loss and Diabetes insipidus due to a silent corticotroph adenoma. Conclusion: SCA’s have more aggressive course and increased rate of recurrence compared to other non-functioning tumors. Diabetes insipidus can rarely be associated with macroadenomas and thus such atypical presentation should also be kept in mind. 

Keywords: Corticotroph adenoma; Diabetes insipidus; Silent; Pituitary.


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